降胆固醇红曲霉菌株的选育及其生物学特性研究  

Study on Screening of Monascus Strain with Producing Blood-Lipids Lowering and Its Biological Characteristics

作　　者：刘德海[1] 何蔚荭[1] 王红云[1] 王健 向凌云[1] 

机构地区：[1]河南省科学院生物研究所,郑州450008 [2]郑州第五人民医院,郑州450003

出　　处：《河南科学》2008年第8期928-930,共3页Henan Science

基　　金：河南省预研专项资金项目(0641180201)

摘　　要：以实验室保藏的红色红曲霉菌株(Monascus ruber)M5为出发菌株,经过紫外线诱变筛选,得到一株产降胆固醇红曲霉功能性菌株N7,并对该菌株的生物学特性进行了研究,认为该菌株具有较好的遗传稳定性和较强的耐乙醇能力,并选择出其最适生长温度以及最佳pH值.Spores of a Monascus ruber M5 from the microorganisms preserved was mutated by ultraviolet mutation in our laboratory. And a Monascus strain N7 with high producing blood-lipids lowering was obtained. The biological characteristics of the strain were stndied. The result showed that this strain N7 has stable genotype, the resistance ability to ethanol was high, and selected its optimal raise temperature and initial pH of growth.

关 键 词：红曲霉菌 紫外诱变 洛伐他汀 生物学特性 

分 类 号：Q183.5[生物学—普通生物学]