山梨酰壳聚糖的制备和抗菌活性  

Synthesis and antibacterial activity of sorbyl chitosan

作　　者：金晓晓[1] 王江涛[1] 白洁[2] 

机构地区：[1]中国海洋大学,海洋化学理论与工程技术教育部重点实验室,山东青岛266100 [2]中国海洋大学,海洋环境与生态教育部重点实验室,山东青岛266100

出　　处：《食品工业科技》2009年第5期103-105,108,共4页Science and Technology of Food Industry

基　　金：科技部国际科技合作重点项目(2004DFA03600)

摘　　要：壳聚糖与山梨酰氯在超声波振荡下,经酰化反应合成了山梨酰壳聚糖衍生物。红外光谱结果表明,产物具有山梨酰壳聚糖的结构特征,并具有良好的溶解性能。对大肠杆菌、金黄色葡萄球菌和黑曲霉进行了抗菌活性研究,并绘制了抑菌生长曲线。实验结果表明,该产物对大肠杆菌、金黄色葡萄球菌和黑曲霉都具有一定的抗菌活性,其抗菌活性随浓度的增加而增加。A novel chitosan derivative was synthesized by the reaction of chitosan with sorbyl chloride working under high-intensity ultrasound.The structure of the product was characterized by FIR spectroscopy.The result confirmed that amino groups on chitosan reacted with sorbyl chloride to form the sorbyl chitosan.The antibacterial activities of chitosan and sorbyl chitosan were investigated by assessing the inhibitory rates of Escherichia coil, Staphylococcus aureus and Aspergillus niger.The growth curves were also described.The results indicated that the product had the effect of bacteriostasis and the antibacterial activity increased with increasing the concentration.

关 键 词：壳聚糖 山梨酸 超声波 抗菌作用 

分 类 号：TS202.3[轻工技术与工程—食品科学]