鲑鱼鱼精蛋白酶解产物中抗氧化活性肽的分离纯化研究  

PURIFICATION AND CHARACTERIZATION OF ANTIOXIDATIVE PEPTIDES FROM SALMON PROTAMINE HYDROLYSATE

作　　者：王勇刚[1,2] 朱锋荣[1] 韩福森[1] 王贺瑶[2] 

机构地区：[1]天津天狮集团全球研发中心,天津301700 [2]中国科学院上海药物研究所,上海201203

出　　处：《食品研究与开发》2009年第6期70-72,共3页Food Research and Development

基　　金：“十一五”国家科技支撑计划重点项目(2006BAD27B06)

摘　　要：研究发现鲑鱼鱼精多肽具有较强的羟自由基、DPPH(1,1-二苯基-2-苦基肼)和超氧阴离子清除活性。通过凝胶色谱、离子交换色谱和反相高效液相色谱分离方法,最终分离到一系列具有抗氧化性的肽段。Salmon protamine hydrolysate was found to possess antioxidative activity against hydroxyl, 2, 2- dipheny1-1-picrylhydrazyl and superoxide anion radicals. Through consecutive chromatographic methods including size exclusion, ion exchange chromatography and reverse-phase high performance liquid chromatography （HPLC）, a series of peptide fractions with high antioxidative activities were obtained.

关 键 词：鱼精蛋白 分离纯化 抗氧化活性 多肽 

分 类 号：TQ464.7[化学工程—制药化工]