纳他霉素毒性及生产研究进展  

Toxicity of Natamycin and the Progress of Its Production and Study

作　　者：董贤慧[1] 高维娟[1] 

机构地区：[1]承德医学院病理生理学教研室,河北承德067000

出　　处：《微生物学杂志》2009年第5期73-77,共5页Journal of Microbiology

基　　金：国家科技支撑计划重大项目(2007BAI26B07)

摘　　要：纳他霉素(Natamycin)是一种广谱的多烯大环内酯类抗真菌抗生素。由于它高效的抑菌效果而被广泛应用于食品防腐和真菌引起的疾病的治疗。对纳他霉素抗菌活性、作用机制、毒性、特别是当前纳他霉素的生产研究状况进行综述。Natamycin is a broad spectrum polyene maerolide antifungal antibiotic. Because of its highly effective antiseptic effects it has been widely used in food preservation and the control of diseases caused by fungi. The antibiotic activity, action mechanism, toxicity, especially current production and study of natamycin were summarized in this paper.

关 键 词：生物防腐剂 纳他霉素 生物合成 发酵 

分 类 号：R931.6[医药卫生—生药学]