基于机器人机构学的蛋白质多肽链逆运动学研究  

Inverse kinematics of protein polypeptide chain based on robotic mechanisms

作　　者：张红亮[1] 李立[1] 

机构地区：[1]西南交通大学,成都610031

出　　处：《机械设计与制造》2010年第3期145-147,共3页Machinery Design & Manufacture

基　　金：四川省应用基础研究项目(2008JY0063)

摘　　要：精确的二面角值对蛋白质分析同源建模法意义重大。将机器人机构逆运动学求解的方法引入蛋白质多肽链的研究,通过建立蛋白质多肽链的机构学模型,给出了蛋白质多肽链中二面角的定义和计算方法,数值实验结果证明了该方法的有效性。开辟了用机构学方法解决生物学问题的新途径。Precise results of dihedral angles are important to homology modeling method in protein analysis. The method of inverse kinematics for robotic mechanism is introduced to the research of protein polypeptide chain to obtain the dihedral angles precisely. Based on the mechanism model of protein polypeptide chain,the definition and calculation method for the dihedral angles are presented. Numerical results illustrate t the efficiency of the method proposed. This study provides a novel way to solve the biological problems by the methods of robotic mechanism.

关 键 词：同源建模法 多肽链 二面角 机构学 

分 类 号：TH12[机械工程—机械设计及理论] TP24[自动化与计算机技术—检测技术与自动化装置]