叶黄素对老年性黄斑变性预防及治疗作用的Meta分析  

Role of lutein in preventing/slowing down age-related macular degeneration： a Meta-analysis

作　　者：张福东[1] 王俐[1] 蔡美琴[1] 

机构地区：[1]上海交通大学医学院营养系,200025

出　　处：《中华临床营养杂志》2010年第2期126-130,I0001,共6页Chinese Journal of Clinical Nutrition

摘　　要：目的评价叶黄素对老年性黄斑变性（AMD）的预防及治疗作用。方法采用电子检索、手工检索及索引检索方式检索所有叶黄素对AMD预防及治疗作用的病例对照研究、队列研究的中英文研究文献，对纳入文献进行质量评价后提取数据信息，采用专用软件RevMan4．2完成系统评价过程。结果共纳入9篇临床研究，合并OR为0．81（0．71，0．92）。结论叶黄素可以在一定程度上预防AMD的发生或延缓其发展。Objective To evaluate the role of lutein in preventing and slowing down age-related macular degeneration （AMD）. Methods Literatures concerning lutein and AMD were colleeted by computerized search, manual search, expert consultations. The quality of included studies was evaluated. RevMan software 4. 2 was used for meta-analysis. Results Totally 9 studies were included, with a total OR of 0. 81 （ range： 0.71- 0. 92）. Conelasioa Lutein can, to some extent, prevent or slow down AMD.

关 键 词：叶黄素 老年性黄斑变性 META分析 

分 类 号：R774.5[医药卫生—眼科]