2007年北京地区母乳中多溴联苯醚污染水平的分析  

Polybrominated dipenyl ethers(PBDEs) in breast milk samples from Beijng in 2007

作　　者：赵云峰[1] 张锐[2] 张磊[1] 李敬光[1] 吴永宁[1] 沈建忠[3] 

机构地区：[1]中国疾病预防控制中心营养与食品安全所 [2]北京市疾病预防控制中心 [3]中国农业大学动物医学院,北京100193

出　　处：《卫生研究》2010年第3期326-330,共5页Journal of Hygiene Research

基　　金：国家自然科学基金课题(No.20837003);国家“十一五”科技支持计划课题(No.2007BAC27B02);863课题(No.2008AA062504)

摘　　要：目的调查北京地区母乳中多溴联苯醚(PBDEs)的污染水平,评价一般人群PBDEs机体负荷状况。方法在北京的城区、近郊区和远郊区分别随机采集母乳样品,以建立的高分辨气相色谱-高分辨质谱法(HRGC-HRMS)测定母乳样品中PBDEs含量,测定组分包括BDE28、BDE47、BDE99、BDE100、BDE153、BDE154和BDE183。结果北京地区母乳中PBDEs各组分均有检出,其中BDE28、BDE47和BDE153三个组分的贡献率约占PBDEs总量(∑PBDEs)的80%。∑PBDEs平均含量为1.48ng/g,中位数含量为1.51ng/g,城区母乳中PBDEs含量高于偏远的农村地区。结论北京地区母乳中PBDEs处于低水平,但是个别样品存在异常污染现象。Objective To evaluate the burden of polybrominated diphenyl ethers（PBDEs） in general people and the exposure of infants via breast feeding in Beijing,the levels of PBDEs in human milk samples from Beijing were investigated.Method Seven congeners of PBDE,including BDE28,BDE47,BDE99,BDE100,BDE153,BDE154 and BDE183 in pooled breast milk samples and 40 individual breast milk samples,were measured with HRGC-HRMS.Result Seven selected congeners of PBDEs were all detected in samples.The mean and median concentration was 1.48ng /g and 1.51ng /g respectively.BDE47,BDE153 and BDE28 were the predominant congeners,accounted for 80% of total PBDEs.PBDEs in breast milk from urban areas were higher than that from rural areas.Conclusion PBDEs in breast milk samples from Beijing were much lower than that from other areas.Further monitoring will be important to determine the variation of PBDE levels and elucidate the contamination status.

关 键 词：母乳监测 多溴联苯醚 机体负荷 环境毒理 

分 类 号：R741[医药卫生—神经病学与精神病学]