烹调油烟冷凝物对小鼠细胞免疫及免疫监视功能的影响  

Effects of cooking oil fume condensate on cellular immunity and immunosurveillance in mice

作　　者：张文宇[1,2] 赵西龙[1,2] 雷志明 宋向东[1,2] 秦钰慧[1,2] 

机构地区：[1]中国预防医学科学院环境卫生监测所 [2]北京医科大学免疫毒理室

出　　处：《卫生研究》1999年第1期18-20,共3页Journal of Hygiene Research

基　　金：中国烟草总公司资助

摘　　要：昆明种雌性小鼠皮下注射经动式染毒装置制备的豆油、菜籽油以及精炼色拉油油烟冷凝物。发现当皮下注射菜籽油油烟冷凝物后，与溶剂对照组相比，低剂量（１．１３ｇ／ｋｇ）菜籽油油烟冷凝物使动物迟发型变态反应明显下降。高剂量使小鼠迟发型变态反应和自然杀伤细胞活性明显下降。皮下注射高剂量（２．２６ｇ／ｋｇ）豆油油烟冷凝物后，小鼠迟发型变态反应、自然杀伤细胞活性和钙调素水平下降，并均具有显著性意义。动物在皮下注射低剂量色拉油油烟冷凝物后，与对照相比动物迟发型变态反应和自然杀伤细胞活性明显下降。本文结果表明。Institute of Environmental Health Monitoring,Chinese Academy of Preventive Medicine,Beijing\ 100021,China Rapeseed oil fume,soyabean oil fume and salad oil fume condensate were injected respectively to female Kunming mice.The results showed that,compared to control group,in mice exposed to low level of rapeseed oil fume condensate,the delayed hypersensitivity responses were inhibited,while in mice exposed to high level of that,the delayed hypersensitivity responses and the NK cells activity were inhibited. In mice exposed to high level of soyabean oil fume condensate the delayed hypersensitivity responses,the NK cells activity and CaM activity were inhibited.The results of these parameters were all statistically significantly different from those in control mice.In mice exposed to low level of salad oil fume condensation,the delayed hypersensitivity responses and the NK cells activity were significantly inhibited.The results indicated that cooking oil fume could affect immune system of animals.

关 键 词：烹调油烟冷凝物 细胞免疫 免疫监视 厨房 油烟 

分 类 号：R126.8[医药卫生—环境卫生学] R513.032[医药卫生—公共卫生与预防医学]