响应面法优化微胶囊补铁剂的制备工艺参数  

Use of Response Surface Methodology to Optimize Hemoglobin Microencapsulation

作　　者：于长青[1] 王长瑞[1] 姚美娜[1] 

机构地区：[1]黑龙江八一农垦大学食品学院,黑龙江大庆163319

出　　处：《食品科学》2010年第12期58-61,共4页Food Science

基　　金：黑龙江省"十一五"科技攻关项目(GB06B403-1-2);黑龙江省科技厅攻关计划项目(GB04B404-04)

摘　　要：利用响应面分析法对微胶囊补铁剂的影响因素,微胶囊的壁材质量与芯材体积之比、预冻时间和壁材质量浓度3个因素进行优化。结果表明,壁材质量与芯材体积之比为19.5:1(g/mL)、壁材质量浓度为9.8g/100mL和预冻时间13.0h,血红素微胶囊的包埋率为92.2%。Central composite design followed by multiple regression analysis and response surface analysis was employed to optimize hemoglobin microencapsulation. The results showed that the optimum conditions for hemoglobin microencapsulation were as follows： wall material-to-core material ratio 19.5：1 （g/mL）, wall material concentration 9.8 g/100 mL and length ofprefreezing time 13.0 h. Under such conditions, the embedding ratio of hemoglobin was 92.2%.

关 键 词：血红素 微胶囊 优化 响应面法 

分 类 号：TS202.3[轻工技术与工程—食品科学]