流感疫苗与格林-巴利综合征  

Influenza Vaccine and Guillan-Barré Syndrome

作　　者：刘东辉[1] 吴星[2] 王军志[2] 汪兴太[1] 

机构地区：[1]美国马塞诸塞公共卫生部实验科学局 [2]中国药品生物制品检定所,北京100050

出　　处：《中国生物制品学杂志》2010年第11期1267-1270,共4页Chinese Journal of Biologicals

摘　　要：格林-巴利综合征(Guillan-Barré syndrome,GBS)是微生物(细菌和病毒等)感染或其他因素诱导所致的针对外周神经系统脱髓鞘炎的自身免疫反应。大范围接种H1N1流感疫苗所致严重GBS已引起人们对流感疫苗罕见不良反应的关注。本文就GBS的历史、临床特征、研究现状、与流感疫苗的相关性、流感疫苗接种的意义及其不良反应监控等作一综述。Guillan-Barre syndrome（GBS）is referred to as acute inflammatory demyelinating polyneuropathy,which is usually caused by microbial,bacteria,viruses or other factors.The adverse effects including GBS emerging from the wide inoculation of H1N1 influenza vaccines have been receiving wide concerns.This paper reviews the history,clinical features,research status of GBS and its relationship to influenza vaccine inoculation,as well as the significance and risk management of influenza vaccination.

关 键 词：流感疫苗 格林-巴利综合征 流感病毒 

分 类 号：R745.43[医药卫生—神经病学与精神病学]