饲喂羊肉和鸭肉日粮对大鼠血清甲状腺素水平的影响  

Effects of sheep meat and duck meat supplemented diets on rat thyroid hormone levels

作　　者：张英君[1,2] 魏法山 李春保[1] 冯宪超[1] 邓宇[1] 闫振国[1] 周光宏[1] 徐幸莲[1] 

机构地区：[1]南京农业大学困家肉品质量安全控制工程技术研究中心,江苏南京210095 [2]南阳师范学院生命科技学院,河南南阳473061 [3]河南省产品质量监督检验院,河南郑州450004

出　　处：《南京农业大学学报》2011年第1期128-132,共5页Journal of Nanjing Agricultural University

基　　金：公益性行业科技专项资金项目(200903012);国际科技合作项目(2009DFA31770)

摘　　要：将40只大鼠随机均分为4组,分别饲喂羊肉、鸭肉、豆粕(对照组)和普通日粮(对照组),采用放射免疫分析法(RIA)测定血清四碘甲腺原氨酸(T4)、三碘甲腺原氨酸(T3)、促甲状腺激素(TSH)、游离四碘甲腺原氨酸(FT4)、游离三碘甲腺原氨酸(FT3)水平和大鼠肝脏Ⅰ型甲状腺原氨酸脱碘酶(5′-脱碘酶)活性的变化,并测量大鼠直肠温度。结果显示:饲喂羊肉的大鼠体温升高,第29天达到(38.66±0.37)℃,显著高于饲喂鸭肉组大鼠体温(38.01±0.55)℃;饲喂羊肉组大鼠血清中T3、T4和FT3、FT4升高,分别达到(0.44±0.10)、(76.29±30.97)ng.mL-1和(7.74±1.75)、(4.37±1.88)pmol.mL-1);饲喂鸭肉组分别为(0.37±0.12)、(42.38±20.05)ng.mL-1和(5.50±1.98)、(3.76±1.63)pmol.mL-1,两组差异显著(P<0.05)。饲喂鸭肉组大鼠血清TSH水平((1.35±0.29)MIU.L-1)显著高于饲喂羊肉组大鼠血清TSH水平((1.01±0.22)MIU.L-1)(P<0.05)。结论:饲喂羊肉能明显促进大鼠甲状腺素分泌,饲喂鸭肉在一定程度上降低大鼠甲状腺素水平。To investigate effects of sheep meat and duck meat supplemented diet on rat thyroid hormone function,40 male rats were randomly assigned to 4 groups：sheep meat supplemented group,duck meat supplemented group,soy protein control group and normal group.After 30 days,levels of 3,3′,5-triiodoehyronine（T3）,3,5,3′5′-tetraiodothyronine（T4）,thyroid stimulating hermone（TSH）,free T3（FT3）and FT4 were detected with the method of radioimmunoassay（RIA）,and body temperatures were measured by thermometer.Results showed that：Body temperature and serum levels of T3,T4,FT3,FT4 increased in sheep meat supplemented group,reaching to（38.66±0.37）℃,（0.44±0.1）ng·mL-1,（76.29±30.97）ng·mL-1,（7.74±1.75）pmol·mL-1 and（4.37±1.88）pmol·mL-1,but decreased in duck meat supplemented group,reaching to（38.01±0.55）℃,（0.37±0.12）ng·mL-1,（42.38±20.05）ng·mL-1,（5.50±1.90）pmol·mL-1 and（3.76±1.63）pmol·mL-1（P0.05）.While,TSH level decreased to（1.01±0.12）MIU·L-1 in sheep meat supplemented group,while increased to（1.53±0.29）MIU·L-1 in duck meat supplemented group（P0.05）.This confirmed that the sheep meat diet increased rat thyroid hormones,while,the duck meat supplemented diet decreased rat thyroid hormones in some degree.

关 键 词：饲喂 羊肉 鸭肉 甲状腺功能 

分 类 号：R581.3[医药卫生—内分泌] Q593.1[医药卫生—内科学]