大蒜辣素对辐射引起的免疫损伤防护作用的研究  

Study on protective effects of allicin on immune injury caused by radiation

作　　者：王鑫[1,2] 吴瑕[2] 朱晓鑫[3] 

机构地区：[1]哈尔滨工业大学化工学院,黑龙江哈尔滨150090 [2]东北农业大学成栋学院,黑龙江哈尔滨150030 [3]东北农业大学资源与环境学院,黑龙江哈尔滨150030

出　　处：《食品工业科技》2011年第2期313-315,318,共4页Science and Technology of Food Industry

摘　　要：构建γ射线辐射模型,考察了辐射对小鼠免疫系统损伤研究的最佳剂量,并研究了大蒜辣素对γ射线辐射引起的小鼠免疫系统损伤的防护效果。结果表明:γ射线对小鼠进行照射的最佳剂量为5Gy。照射前补充大蒜辣素后,以小鼠碳廓清指数、血清溶血素含量、脾指数、DTH足跖增厚程度为免疫系统指标,16mg/kg.d的剂量组可以有效地防护由于γ射线辐射造成的免疫系统损伤。γ-ray radiation model was constructed,radiation damage of the immune system of mice on the optimum dose and the allicin of radiation-induced immune injury of the protective effect were studied. The results showed that the best dose of γ-ray irradiation of mice was 5Gy. Added allicin before irradiation,carbon clearance index,serum hemolysin concentration,spleen index,DTH plantar thickening of the degree as the immune system of indicators,and 16mg/kg·d dose groups can be an effective protective for immune system due to radiation damage.

关 键 词：大蒜辣素 辐射 免疫系统 

分 类 号：TS201.4[轻工技术与工程—食品科学]