摄食鱿鱼对人体血脂的影响  

Effect of Dietary Squid on Serum Lipid in Healthy Human

作　　者：王玉明[1] 杜磊[1] 任兵兴[1] 薛勇[1] 李兆杰[1] 薛长湖[1] 

机构地区：[1]中国海洋大学食品科学与工程学院,山东青岛266003

出　　处：《食品科学》2011年第7期286-288,共3页Food Science

基　　金：国家自然科学基金项目(30972285);国际科技合作项目(2010DFA31330)

摘　　要：探讨高胆固醇海产品的摄食对正常人群血脂的影响。选取33名年龄在22～28岁之间的健康实验人员,每天食用100g鱿鱼,持续20d,并测定实验开始时、10d及20d后,血脂、血糖、肝功能指标以及血清脂肪酸组成的变化。结果显示:每日摄入100g鱿鱼,可明显降低受试者血清甘油三酯(TG)浓度(降低18%,P<0.004),但对血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、血糖浓度及肝功能标志酶活性均无显著影响。摄食鱿鱼后血清总脂肪酸组成发生明显变化,血清中二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)显著增加。提示每日100g鱿鱼的摄入不会影响健康人群血清胆固醇浓度,对动脉粥样硬化不具危险性。In order to investigate the effect of high-cholesterol seafood intake on serum lipid in healthy human,thirty-three healthy volunteers aged from 22 to 28 years including 16 males and 17 females were given 100 g of dietary squid daily for 20 consecutive days.Blood samples were collected on days 0,10 and 20 of the trail to assay serum lipid,blood glucose,liver function index and fatty acid composition.The results showed that the intake of dietary squid could result in a significant decrease in serum TG level after 9 days.Serum total cholesterol（TC）,low-density lipoprotein cholesterol（LDL-C）,high-density lipoprotein cholesterol（HDL-C） and glucose level were not changed due to the intake of dietary squid.Meanwhile,dietary squid markedly changed serum fatty acid composition,and significantly increased EPA and DHA levels.These findings revealed that the intake of dietary squid at the dose of 100 g/d has no effect on serum cholesterol concentration in normal human,suggesting that squid consumption should not be a cause of arteriosclerosis.

关 键 词：鱿鱼 胆固醇 甘油三酯 血脂 营养干预 动脉硬化 

分 类 号：R459.3[医药卫生—治疗学]