叶黄素-β-环糊精包合物的制备及其光谱研究  

Preparation and Spectral Studies of Lutein-β-cyclodextrin Inclusion

作　　者：张多婷[1] 韩静[1] 项文娟[1] 张玥[1] 

机构地区：[1]沈阳药科大学制药工程学院,辽宁沈阳110016

出　　处：《食品科学》2011年第17期199-203,共5页Food Science

基　　金：沈阳市科技局大型仪器共享项目(2008gx-006);辽宁省教育厅科学技术研究项目(2009A868)

摘　　要：以β-环糊精(β-CD)为主体,超声法制备叶黄素β--环糊精(叶黄素-β-CD)包合物,通过X射线粉末衍射光谱、红外光谱及差示扫描量热分析对叶黄素-β-CD包合物进行表征。结果表明:叶黄素-β-CD包合物的适宜包合条件为叶黄素与β-CD的物质的量比1:4,超声功率400W,超声时间40min,包合率可达到75.8%以上;产物的光谱特征的变化证实叶黄素和β-CD形成了新的物相;而用相溶解度确定叶黄素和β-CD的相溶解度曲线属于AL型,叶黄素与β-CD形成1:1包合物,包结常数为346.97L/mol。经包合后,叶黄素的稳定性与水溶性得到明显提高。β-cyclodextrin was used as the host to prepare lutein-β-cyclodextrin inclusion by means of ultrasonic.The structure of lutein-β-cyclodextrin inclusion was characterized by Fourier transform infrared spectroscopy,differential scanning calorimetry,and X-ray diffraction spectroscopy.The results indicated that the optimal inclusion conditions were lutein-to-β-cyclodextrin ratio of 1：1,ultrasonic power of 400 W,and ultrasonic treatment time of 40 min.Under the optimal inclusion conditions,the yield of lutein-β-cyclodextrin was 75.8%.The spectral characteristics of the product revealed that lutein and β-cyclodextrin could form inclusion with a ratio of 1：1 and the inclusion constant was 346.97 L/mol.The stability and water solubility of lutein was significantly increased through the inclusion reaction.

关 键 词：叶黄素 Β-环糊精 包合物 包结常数 

分 类 号：TS218[轻工技术与工程—粮食、油脂及植物蛋白工程]