Immunoregulatory Effects of Indomethacin on Rats with Trauma　  

作　　者：潘永成 张寿熙 丁显仲 李桦 

出　　处：《Journal of Huazhong University of Science and Technology(Medical Sciences)》1995年第4期234-237,共4页华中科技大学学报（医学英德文版）

摘　　要：In this article, we invertigated changes of immune functions and immunoregulatory effects of indomethacin on rats with trauma. The results show that spontaneous suppressor T cell activity of spleen significantly increased and Interleukin 2 production and DNA synthesis capacity of splenocytes markedly decreased in rats with trauma. Indomethacin could markedly improve immune function , decreased spontancous suppressor T cell activity and prompted Interleukin 2 production and DNA synthesis capacity of splenocytes.In this article, we invertigated changes of immune functions and immunoregulatory effects of indomethacin on rats with trauma. The results show that spontaneous suppressor T cell activity of spleen significantly increased and Interleukin 2 production and DNA synthesis capacity of splenocytes markedly decreased in rats with trauma. Indomethacin could markedly improve immune function , decreased spontancous suppressor T cell activity and prompted Interleukin 2 production and DNA synthesis capacity of splenocytes.

关 键 词：TRAUMA spontaneous suppressor T cell interleukin 2 IMMUNOREGULATION INDOMETHACIN 

分 类 号：R730.3[医药卫生—肿瘤]