Morphometric study of endothelial wound-healing following penetrating keratoplasty  

作　　者：蒋华 宋振英 林庆华 

机构地区：[1]Department of Ophthalmology,Jinan General Hospital of PLA,Jinan,250031 [2]Software Department,Langchao Corp,Jinan,250013

出　　处：《Journal of Medical Colleges of PLA(China)》1993年第3期291-295,共5页中国人民解放军军医大学学报（英文版）

摘　　要：Twenty samples of endothelia removed from normal and post penetrating keratoplas-ty (0.5,1,2,3 months after penetrating keratoplasty) were observed by scanning electron mi-croscopy.The photographs of the endothelia in graft-host junction were analyzed by computer-assisted image analysis system,and the morphometric indexes examined were area of the cells,perimeters,density,figure coefficient,long axis,coefficient of variation of the area,and oth-ers.Results showed that the morphology and the density of the endothelial cells changed obvi-ously after operation and improved slowly but progressively with time although at 3 monthspostoperatively some differences still existed.By using the new techniques,the experiment con-firmed and enriched the theories on the corneal endothelial wound-healing,revealing some ofthe new characters of the endothelial wound-healing following penetrating keratoplasty.Twenty samples of endothelia removed from normal and post penetrating keratoplas- ty (0.5,1,2,3 months after penetrating keratoplasty) were observed by scanning electron mi- croscopy.The photographs of the endothelia in graft-host junction were analyzed by computer- assisted image analysis system,and the morphometric indexes examined were area of the cells, perimeters,density,figure coefficient,long axis,coefficient of variation of the area,and oth- ers.Results showed that the morphology and the density of the endothelial cells changed obvi- ously after operation and improved slowly but progressively with time although at 3 months postoperatively some differences still existed.By using the new techniques,the experiment con- firmed and enriched the theories on the corneal endothelial wound-healing,revealing some of the new characters of the endothelial wound-healing following penetrating keratoplasty.

关 键 词：KERATOPLASTY PENETRATING CORNEAL ENDOTHELIUM wound healing MORPHOMETRY rabbits 

分 类 号：R[医药卫生]