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作品数:264被引量:353H指数:7
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相关领域:医药卫生更多>>
相关作者:柴峰马嵩王广科李静波朱倩倩更多>>
相关机构:中国药科大学学研究院河南省中医院河南省人民医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Brain-penetrating neurotrophic factor mimetics: HER-096 as a disease-modifying therapy for Parkinson’s disease
《Neural Regeneration Research》2025年第4期1094-1095,共2页Natalia Kulesskaya Kira M.Holmström Henri J.Huttunen 
supported by Herantis Pharma Plc and the European Innovation Council(grant acronym ReTreatPD).
Neurotrophic factors as a therapeutic approach in neurodegenerative diseases:A major unmet need in the field of central nervous system diseases is disease-modifying treatments.While for decades there have been various...
关键词:DISEASES treatment THERAPEUTIC 
Multidetector computed tomography angiography for diagnosis of traumatic aneurysms associated with penetrating head injuries
《Chinese Journal of Traumatology》2025年第2期91-95,共5页Babichev Konstantin Nickolaevich Savello Aleksandr Viktorovich Isaeva Alla Vladimirovna Svistov Dmitrij Vladimirovich Men'kov Igor'Anatol'evich Isaev Dzhamaludin Magomedrasulovich 
Purpose:To analyze the diagnostic efficacy of computed tomography angiography compared to digital cerebral angiography for the diagnosis of traumatic aneurysms(TAs)associated with combat-related penetrating head injur...
关键词:Traumatic aneurysm Multidetector computed tomography angiography Digital cerebral angiography Penetrating injury 
Anti-migration of NG by using EPDM insulation materials coated with reduced graphene oxide
《Defence Technology(防务技术)》2025年第3期109-118,共10页Liyun Lin Lipeng Sang Yiheng Li Jiawei Yan Panpan Peng Qilong Yan Bowen Tao Xiang Guo 
National Natural Science Foundation of China(Grant No.22175059)to provide fund for conducting experiments.
The migration of nitroglycerin(NG) has always been the critical issue that harmfully impacts the structural integrity and operational reliability of the solid rocket motor, which is mainly composed by Nitrate Ester Pl...
关键词:Impermeability of graphene Swelling effect of toluene Penetrating effect of RGO Anti-migration performance to NG 
Response properties of geometries of coal penetrating fracture on seepage behavior
《International Journal of Mining Science and Technology》2025年第2期191-211,共21页Penghua Han Kai Wang Jiewen Pang Xiaofeng Ji Cun Zhang 
supported by the National Natural Science Foundation of China (Nos. 52474161, and 52404093);Fundamental Research Program of Shanxi Province (Nos. 202303021222168 and 202203021221143);Taiyuan University of Science and Technology Scientific Research Initial Funding (No. 20242103);the Postdoctoral Research Foundation of China(No. 2023M733778)。
The fracture surfaces of coal-rock masses formed under mining-induced stress generally exhibit complex geometries, and the fracture geometry is one of the primary factors affecting the seepage characteristics of coal-...
关键词:Coal penetrating fracture ROUGHNESS GEOMETRIES Seepage characteristics 
Recognition for underground voids in C-scans based on GMM-HMM
《Journal of Systems Engineering and Electronics》2025年第1期82-94,共13页BAI Xu LI Yuhao GUO Shizeng LIU Jinlong WEN Zhitao LI Hongrui ZHANG Jiayan 
National Natural Science Foundation of China(62071147)。
Ground penetrating radar(GPR),as a fast,efficient,and non-destructive detection device,holds great potential for the detection of shallow subsurface environments,such as urban road subsurface monitoring.However,the in...
关键词:ground penetrating rader(GPR) RECOGNITION edge histogram descriptor(EHD) histogram of oriented gradient(HOG) Log-Gabor filter 
Perspectives on additive manufacturing for warhead applications
《Defence Technology(防务技术)》2025年第1期225-251,共27页Hao Xue Qiang Zhou Chuan Xiao Guangyan Huang 
sponsored by the National Key Research and Development Program of China(Grant No.2022YFC3320500);the National Natural Science Foundation of China(Grant Nos.12372333,12221002 and 12072037)。
According to different damage modes,warheads are roughly divided into three types:fragmentation warheads,shaped charge warheads,and penetrating warheads.Due to limitations in material and structural manufacturing,trad...
关键词:Additive manufacturing Fragmentation warhead Shaped charge warhead Penetrating warhead Warhead charge 
An inner shelf penetrating front and its potential biogeochemical effects in the East China Sea during October
《Acta Oceanologica Sinica》2024年第11期1-11,共11页Hui Ding Qinsheng Wei Ming Xin Yuhang Zhao Bin Zhao Mingyu Wang Fei Teng Xuehai Liu Baodong Wang 
The National Natural Science Foundation of China under contract Nos U23A2033 and 41876085;the Basic Scientific Fund of the National Public Research Institutes of China under contract No.2020S03.
Based on in-situ observations in the East China Sea(ECS)during October 2021,we investigated a cross-shelf penetrating front(PF)in the inner shelf and explored its potential biogeochemical-ecological effects from a mul...
关键词:penetrating front biogeochemical effects NUTRIENT chlorophyll a East China Sea 
Penetrating efficiency of supramolecular hydrogel eye drops:Electrostatic interaction surpasses ligand-receptor interaction
《Chinese Chemical Letters》2024年第11期419-422,共4页Zhibin Ren Shan Li Xiaoying Liu Guanghao Lv Lei Chen Jingli Wang Xingyi Li Jiaqing Wang 
supported by National Natural Science Foundation of China(Nos.82102215 and 82372129);Wenzhou Medical University Scientific Research Fund(No.KYQD20210602)。
The low drug bioavailability of eye drops challenges the therapy of ocular disorders with high efficacy.One of solutions is to extend the corneal retention and enhance the penetration of drug into cornea.Here we synth...
关键词:Supramolecular hydrogel Eye drop Electrostatic interaction Ligand-receptor interaction Corneal penetration 
Etiology and Surgical Management of Penetrating Arterial Trauma of Limbs in Toamasina
《World Journal of Cardiovascular Surgery》2024年第11期181-190,共10页Medyno Lovasoa Mampiadana Fanomezantsoa Raherinantenaina Zakarimanana Lucas Randimbinirina Andriamihaja Jean-Claude Rakotoarisoa Toky Mamin’ny Aina Rajaonanahary 
Background: The prevalence of penetrating arterial trauma of limbs remains unknown in Toamasina. Their management remains a challenge due to lack of protocol and late in admission of victims. The aim of this study was...
关键词:ARTERY Vascular Injury LIMBS Surgery TRAUMA 
Patterns and mechanism of wintertime penetrating fronts in the East China Sea
《Science China Earth Sciences》2024年第11期3500-3514,共15页Peng YE Daji HUANG Jiliang XUAN Shuangyan HE 
supported by the National Natural Science Foundation of China (Grant Nos. 42230404 & 42276021);the National Key R&D Program of China (Grant Nos. 2022YFC3103402 & 2023YFD2401904);the Zhejiang Provincial Natural Science Foundation of China (Grant No. LY21D060003);the high-performance computing cluster of the State Key Laboratory of Satellite Ocean Environment Dynamics。
Penetrating fronts play an important role in the cross-shelf transport of terrestrial materials in the East China Sea(ECS). Using long-term satellite remote sensing data and numerical simulation data, the most likely ...
关键词:Penetrating fronts Satellite-derived chlorophyll Lagrangian tracer experiments Synoptic-scale fluctuation Western Kuroshio Branch 
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