藻胆蛋白提取纯化及生理活性研究进展(英文)  

Research Progress in Extraction,Purification and Physiological Activity of Phycobiliprotein

作　　者：程超[1,2] 薛峰[2] 汪兴平[1] 潘思轶[2] 

机构地区：[1]湖北民族学院生物科学与技术学院,湖北恩施445000 [2]华中农业大学食品科技学院,湖北武汉430070

出　　处：《食品科学》2012年第9期251-259,共9页Food Science

基　　金：国家自然科学基金项目(30970284)

摘　　要：藻胆蛋白是一类结构相似的色素蛋白,它们是由藻胆色素与相应的脱辅基蛋白中保守性半胱氨酸残基的巯基以硫醚键共价结合而成,藻胆蛋白由于其荧光特性广泛应用在医药行业。本文综述藻胆蛋白的种类和结构,藻胆蛋白的提取过程尤其是细胞破碎、纯化的方法,并详细比较其优缺点;阐述藻胆蛋白的抗氧化、抗炎及抗癌作用,并对其部分作用机制进行综述。Phycobiliproteins are a group of pigment proteins with similar structures, which are formed through a covalent thioether bond between phycobilin and sulfhydryl （-- SH） groups in conservative cysteine residues. Due to its fluorescence, phycobiliprotein is widely used in the pharmaceutical industry. In this article, the classification and structure of phycobiliprotein, extraction procedures and purification are described. In addition, the anti-oxidant, anti-inflammatory and antitumor functions of phycobiliprotein as well as corresponding mechanisms are discussed. According to current studies, many efforts still need to be made for seeking potential resources and food functions of phycobiliprotein.

关 键 词：藻胆蛋白 细胞破碎 纯化 生理活性 机制 

分 类 号：R284.2[医药卫生—中药学]