海洋宏基因组学研究进展  

Research Advance in Marine Metagenomics

作　　者：王晓辉[1,2,3] 张庆芳[2] 迟乃玉[2] 曹海龙[1] 赵勇[1] 杜昱光[1] 

机构地区：[1]中国科学院大连化学物理研究所天然产物与糖工程组辽宁省碳水化合物研究重点实验室,大连116023 [2]大连大学生命科学与技术学院,大连116622 [3]中国科学院研究生院,北京100049

出　　处：《生物技术通报》2012年第7期32-35,共4页Biotechnology Bulletin

基　　金：国家"863"计划重点项目(2011AA090704)

摘　　要：宏基因组学作为研究微生物种群生态分布、群体遗传特征和基因相互作用的新兴学科,在未培养微生物资源的开发利用上取得了突破性进展,已成为海洋等极端环境中分离与鉴定新型工业酶制剂的有效工具。综述海洋宏基因组学研究进展,以及宏基因组学领域中如新一代测序技术等,以期为从海洋环境中开发具有工业潜力和应用价值的新型生物催化剂提供参考。As a new scientific field of studying gene function and interactions of microbial community, metagenomics has made breakthrough progress in the development and utilization of cultivation-independent microbial resources. Metagenomic based strategies have been successfully employed as powerful tools to isolate and identify novel enzymes with industrial applications. In this review, an overview of the different applications of metagenomics was given, and an outline of the recent advances in this fast-developing field was discussed, including next-generation sequencing technology. We hope to provide the reference about the industrial potential and the application value of novel biocatalyst from the marine environments.

关 键 词：宏基因组学 文库筛选 新一代测序技术 海洋 

分 类 号：Q933[生物学—微生物学]