烟雾病的遗传学研究进展  

Advances in the genetics of moyanmya disease

作　　者：王筱萌[1] 黄显军[1] 徐格林[1] 

机构地区：[1]南京大学医学院临床学院,南京军区南京总医院神经内科,210002

出　　处：《国际脑血管病杂志》2012年第7期508-512,共5页International Journal of Cerebrovascular Diseases

摘　　要：烟雾病（moyamoya disease，MMD）是一种少见的脑血管病，在东亚地区的发病率较高。MMD的发病机制目前仍不明确，但流行病学研究提示遗传因素在MMD发病中具有重要作用。文章就MMD相关基因的研究进展进行了简要综述。Moyamoya disease is a rare cerebrovascular disease. Its incidence is higher in the East Asia. The pathogenesis of MMD remains unclear at present, but the epidemiological research both at home and abroad suggests that the genetic factors play an important role in the onset of MMD. This article briefly reviews the recent progress in research on MMD related genes.

关 键 词：烟雾病 疾病遗传易感性 多态现象 遗传学 全基因组关联研究 

分 类 号：R743.3[医药卫生—神经病学与精神病学]