败酱草提取物的降血脂作用研究  

Study of Blood Lipid-lowering Effect of Herba patriniae

作　　者：兰桃芳[1] 卢佳琨[1] 渠宏雁[1] 刘锦峰[1] 蔡文倩[1] 孟良玉[1] 

机构地区：[1]渤海大学化学化工与食品安全学院,辽宁省食品安全重点实验室,辽宁省高校重大科技平台"食品贮藏加工及质量安全控制工程技术研究中心",辽宁锦州121013

出　　处：《现代食品科技》2012年第9期1120-1122,共3页Modern Food Science and Technology

基　　金：辽宁省科技厅博士启动项目(20111146)

摘　　要：为研究败酱草对大鼠脂类代谢的影响,采用SD大鼠(雌雄各半),对动物进行编号并随机分成4组,采用高脂饲料喂养小鼠建立高脂血症模型,喂养4周后,测定总胆固醇(TC)为3.01、总甘油三酯(TG)为1.36、高密度脂蛋白胆固醇(HDL-c)为0.32、低密度脂蛋白胆固醇(LDL-c)为1.07,结果表明败酱草提取物对高血脂症老鼠的血脂有显著的改善作用,说明败酱草具有抵抗血脂升高的作用,可作为功能性食品加以开发。To study the influence of Herba Patriniae on lipid metabolism of rats, SD rats （male and female in half and half） were used as experimental animals. The experimental model was established with high-fat feed. Blood fi＇om eyeball was drawn after fed for 4 weeks. The contents of cholesterol （TC）, triglyceride （TG）, low-density lipoprotein cholesterol （LDL-C） and high-density lipoprotein cholesterol （HDL-C） were 3.01, 1.36, 0.32 and 1.07, respectively. Results showed that, compared with the positive control group, the contents of TC, TG LDL-c of the other three groups were much lower and HDL-c was significantly higher. There were remarkable differences among the different dose groups. It was concluded that Herba patn＇niae has action of regulating blood lipids. The Herba patriniae can be used as a functional food to be developed.

关 键 词：败酱草 降血脂 高血脂症 

分 类 号：R285[医药卫生—中药学]