阴离子交换树脂D318分离提取发酵液中的2-酮基-D-葡萄糖酸  

Extraction of 2-Keto-D-gluconic Acid from Fermentation Broth with Weakly Basic Anion Exchange Resin D318

作　　者：余泗莲[1] 周强[1] 余彬[1] 彭化南[2] 郑大贵[2] 

机构地区：[1]百勤异Vc钠有限公司,江西德兴334221 [2]上饶师范学院,江西省普通高校应用有机化学重点实验室,江西上饶334001

出　　处：《化工技术与开发》2012年第10期4-6,48,共4页Technology & Development of Chemical Industry

基　　金：江西省科技条件平台建设项目(2010DTZ01900);江西省优势科技创新团队计划项目

摘　　要：采用弱碱性阴离子交换树脂D318直接吸附发酵液中的2-酮基-D-葡萄糖酸,之后用浓硫酸-甲醇混合液解吸,解吸液直接用于异Vc钠生产的后续酯化环节,简化了工艺流程,提高了效率。探讨了离交液浓度、离交液流速和树脂床高径比对单位树脂吸交量的影响,并结合离子交换原理对有关结果进行了讨论。2-Keto-D-gluconic acid （2-KGA） in fermentation broth was directly adsorbed on the anion exchange resin D318, and was consequently readsorbed by concentrated sulfuric acid - methanol mixture. The readsorbed elution was directly esterified by heat to give methyl 2-Keto-D-gluconate. The above procedures could simplify the process of sodium D-isoascorbate production. The effect of factors such as the concentration of 2-KGA, the flow rate of feed, the ratio of height to dimmer of resin bed on the adsorption capacity of resin was explored. Furthermore, the relevant experimental results were discussed based on the principle of ion exchange.

关 键 词：2-酮基-D-葡萄糖酸 阴离子交换树脂 提取 

分 类 号：TS202.3[轻工技术与工程—食品科学]