油茶粕多肽降血脂活性研究  

Study on Lipidemia-lowering Activities of Oil-tea Sead Meal Peptides

作　　者：龚吉军[1,2] 钟海雁[1,2] 黄卫文[1,2] 王青云[1,2] 唐静[1,2] 黄亮[1,2] 杨自洁[1,2] 

机构地区：[1]稻谷及副产物深加工国家工程实验室,湖南长沙410004 [2]中南林业科技大学食品科学与工程学院,湖南长沙410004

出　　处：《食品研究与开发》2012年第10期24-28,共5页Food Research and Development

摘　　要：通过建立SD大鼠高血脂模型,采用低、中、高三种剂量(250、500、1000 mg/kg.bw),研究了油茶粕多肽(Alcalase水解,MW<3 ku)的降血脂活性。结果表明,低、中、高剂量的油茶粕多肽均可显著降低高血脂模型SD大鼠血清中TC与TG的含量、动脉硬化指数(AI),还能有效提高HDL-C的水平。试验结果提示油茶粕多肽具有良好的降血脂功效,可有效降低动脉粥样硬化的风险。Taking model of hyperlipidemia SD rats as experimental animals,lipidemia-lowering activities of oil-tea sead mael peptides（OTSMP,hydrolysis by alcalase,MW3 ku） were studied by means of three kinds of dose i.e.250,500 and 1000 mg/kg·bw.Results showed that low,medium and high dose of OTSMP could effectively reduce the levels of TC TG,also significantly lessen the value of atherosclerosis index（AI）.All of three doses of OTSMP could obviously increase the level of HDL-C in the serum of model rats.These results suggested that OTSMP had highly lipidemia-lowering effects and could effectively decrease the risk of atherosclerosis.

关 键 词：油茶粕多肽 降血脂活性 SD大鼠模型 

分 类 号：R151[医药卫生—营养与食品卫生学]