反丁烯二酸水杨酸甲酯的合成及抑菌活性研究  

Study on Synthesis and Antimicrobial Activitiy of Glycerine Methyl Salicylate Methyl Fumarate

作　　者：胡鑫鑫[1] 董利[1] 陈颖峰[1] 黄小翰[1] 

机构地区：[1]茂名职业技术学院化学工程系,广东茂名525000

出　　处：《当代化工》2013年第1期14-17,共4页Contemporary Chemical Industry

摘　　要：基于防腐防霉剂构效关系研究,以马来酸酐和甲醇为起始原料,合成出一种具有α、β-不饱和羰基结构的新型食品防腐剂——反丁烯二酸水杨酸甲酯。对其进行抗菌活性研究,结果表明,MSMF的抑菌谱较广,对常见的细菌、酵母、霉菌均具有较强的抑制作用,效果优于常用抗菌剂苯甲酸。此外,试验表明MSMF在不同pH值、不同温度下均能表现出良好的抗菌活性,是一种具有广阔开发前景的抗菌剂。Based on the structure-activity relationship of preservative and mold preventives,a new type of preservatives,methyl salicylate methyl fumarate（MSMF） was synthesized from maleic anhydride and methanol.The antibacterial experiment results show that it can inhibit bacteria,yeast and mycete;And its effect is better than common preservative benzoic acid.Furthermore it can be used under different pH values and different temperatures.So it has a wide prospect of development and application.

关 键 词：反丁烯二酸水杨酸甲酯 防腐剂 合成 抑菌活性 

分 类 号：TS202.3[轻工技术与工程—食品科学]