儿童遗传性肾脏疾病  

Hereditary kidney diseases in children

作　　者：张琰琴[1] 丁洁[1] 王芳[1] 张宏文[1] 

机构地区：[1]北京大学第一医院儿科,北京100034

出　　处：《北京大学学报（医学版）》2013年第2期182-185,共4页Journal of Peking University:Health Sciences

基　　金：国家自然科学基金(30170992;30371495;30400482;30672259;30830105;30801250;30801252);"十一五"(2006BAI05A07)国家科技支撑计划重点项目;"十二五"(2012BAI03B02)国家科技支撑计划重点项目;北京市自然科学基金(7102148)资助~~

摘　　要：近年来随着医学的发展，临床疾病谱也发生了变化，先天性疾病和遗传性疾病正替代传染性疾病成为与心血管疾病、癌症等并列的严重危害人类健康的疾病之一。人类基因组计划的完成和分子诊断技术的进步，有力地推动了医学遗传学的发展。About 10 to 15 percent of kidney diseases are inherited or related to genetic factors. While, hereditary kidney diseases have no specific clinical manifestations and react poorly to the therapy, as a result, about 30 percent of hospitalized children with chronic renal failure is due to hereditary kidney diseases in our country. Hereditary kidney diseases are related to many genes. Molecular genetic analysis plays an important role in the diagnosis and prenatal diagnosis of hereditary kidney diseases. Our group have made a series of research in hereditary kidney diseases for nearly 30 years. Here we review the re-search work and the main results in hereditary kidney diseases of our group.

关 键 词：肾疾病 遗传性疾病 先天性 儿童 肾炎 遗传性 

分 类 号：R726.9[医药卫生—儿科]