角鲨烯和维生素E抗皮肤衰老作用的比较研究  

Comparative study on anti-aging effect of squalene and vitamin E to skin

作　　者：雷茜茜[1,2,3] 赵松林[2,3] 陈卫军[2,3] 宋菲[2,3] 

机构地区：[1]海南大学食品学院,海南海口570228 [2]中国热带农业科学院椰子研究所,海南文昌571339 [3]海南省椰子深加工工程技术研究中心,海南文昌571339

出　　处：《食品工业科技》2013年第13期91-93,98,共4页Science and Technology of Food Industry

基　　金：公益性行业(农业)科研专项(20090326);中央级公益性科研院所基本科研业务费专项(1630052012002)

摘　　要：研究角鲨烯对皮肤的抗衰老作用并与维生素E进行比较。在10%新鲜猪皮匀浆中分别添加体积为20、40、60、80、100μL的角鲨烯和维生素E,测定猪皮组织匀浆中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、过氧化氢酶(CAT)活力,并通过吸光值间接反映了蛋白质羰基和蛋白质氢过氧化物含量变化,以空白作为对照。结果表明角鲨烯能显著提高猪皮SOD、GSH-Px和CAT的活力,同时能显著降低皮肤中蛋白质羰基和蛋白质氢过氧化物含量,且效果较维生素E明显。表明角鲨烯对皮肤有一定的抗衰老作用。Research about anti-aging effect of squalene and vitamin E to skin where they were mixed with 10% fresh pigskin slurry with a volume of 20,40,60,80,1001jL of squalene.The activity of superoxide dismutase （SOD）, glutathione peroxidase（GSH-Px） and catalase （CAT） of the pig skin slurry were evaluated, the absorption value reacted indirectly the change of protein carbonyl groups and protein hydroperoxides content, and the blank as a control.The results showed that squalene could remarkably improve SOD, GSH-Px and CAT activity of the pig skin.It also significantly reduced protein carbonyl groups and protein hydroperoxides content of the pig skin,and the effect of squalene was better than vitamin E.Taken togrther results indicated that squalene had anti-aging effect on the skin.

关 键 词：角鲨烯 维生素E 抗衰老 抗氧化 

分 类 号：TS201.1[轻工技术与工程—食品科学]