不同剂量水蛭粉对高脂饮食兔血脂水平的影响  

Effect of adding different dosage Hirudo nipponica on the level of blood lipids in rabbits fed with high-fat diet

作　　者：罗哲容 苏双良[2] 任慧君[1] 王慧[2] 赵志壮[2] 冷雪冰[3] 白秀娟[2] 

机构地区：[1]东北农业大学生命科学学院,黑龙江哈尔滨150030 [2]东北农业大学动物科学技术学院,黑龙江哈尔滨150030 [3]吉林农业大学中药材学院,吉林长春130118

出　　处：《食品工业科技》2014年第14期359-362,共4页Science and Technology of Food Industry

摘　　要：目的:研究不同剂量水蛭粉对高脂饲料喂养兔血清血脂水平的影响。方法:选择体质健康伊拉肉兔150只,随机分成5组,即空白组、高脂组和三个不同剂量组(0.15、0.075、0.0375g/kg水蛭粉),在实验前、实验第20d和第40d空腹称重,并心脏采血,测定血清中总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)含量。结果:各组体重随时间而增长,实验结束时,各组间体重差异不显著(p>0.05);高脂组TC、TG、LDL-C水平明显高于空白组(p<0.01),HDL-C水平高于空白组,但差异不显著(p>0.05);高、中、低剂量组TC、TG、LDL-C水平明显低于高脂组(p<0.01),高、中、低剂量组之间无显著差异(p>0.05);高、中、低剂量组HDL-C水平与高脂组差异不显著(p>0.05)。结论:水蛭粉能调节高脂饲料喂养过程中兔的血脂水平,对高脂血症起到保健作用,且低剂量水蛭粉(0.0375g/kg)则可达到显著的降血脂效果。Objective：To study the effects of different dosage Hirudo nipponica on the level of blood lipids in rabbits fed with high-fat diet. Methods ：150 male meat rabbits were selected and randomly divided into five groups,control group,high serum lipid group and three different dosage Hirudo groups. Rabbits in Hirudo groups were daily fed with Hirudo （0.15,0.075,0.0375g/kg） for 40 days. The blood samples were drawn from heart just before the experiment and the 20th day,40th day of the experiment. The blood lipids level in serum included total cholesterol （TC）,triglyceride （TG）,high density lipoprotein （HDL-C）,low density lipoprotein （LDL-C）. Results：The body weight of rabbits in each groups was increasing during the test period,but no significant was observed between each groups（p〉0.05）. The blood lipids in high serum lipid group was abnormal,compared with control group,the levels of TC,TG,LDL-C in high serum lipid group were significantly increased （p〈0.01）,the level of HDL-C was higher（p〉0.05）. Compared with high serum lipid group,the level of TC,TG, LDL-C in three Hirudo groups were significant decreased （p〈0.01）,while no significant differences （p〉0.05） were observed between the three Hirudo groups. Compared with high serum lipid group,the level of HDL-C in Hirudo group had no significant differences（p〉0.05）. Conclusion： Hirudo could regulate the blood lipid and prevent the formation of hyperlipidmia,and the lower level Hirudo（0.0375g/kg） could significantly decrease blood lipids.

关 键 词：水蛭 高脂饮食 血脂 兔 

分 类 号：TS201.1[轻工技术与工程—食品科学]