Degrees of Diaphragma Sellae Descent during Transsphenoidal Pituitary Adenoma Resection:Predictive Factors and Effect on Outcome  

作　　者：Ahmed Abdelmaksoud Peng FU Osamah Alwalid Ahmed Elazab Ahmed Zalloom Wei XIANG Xiao-bing JIANG Hong-yang ZHAO 

机构地区：[1]Department of Neurosurgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology Wuhan 430022,China [2]Department of Radiology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China [3]School of Biomedical Engineering,Health Science Center,Shenzhen University,Shenzhen 518060,China [4]Computer Science Department,Misr Higher Institute for Commerce and Computers,Mansoura 11001,Egypt

出　　处：《Current Medical Science》2018年第5期888-893,共6页当代医学科学（英文）

摘　　要：This study is aimed to classify degrees of diaphragma sellae (DS) descent into sella turcica according to the surgical field block caused by the descent and to construct predictive imaging criteria for the degree of descent,and in addition,to determine whether there is any correlation between the degree of DS descent and the operative outcome (in the form of cerebrospinal fluid leak and/or presence of residual tumor).Totally,72 patients were enrolled in our study.Their clinical and radiological data as well as the high definition videos of operations were retrospectively reviewed.The degree of DS descent during the operation was classified into five degrees according to surgical field block caused by the descent.We investigated the correlation between these five degrees and the clinical findings,radiological findings as well as the surgical outcomes.We found that the most important determining factors of DS descent degree were the volume and the height of the tumor portion above diaphragma opening.On the other hand,the total tumor volume,the maximum tumor height and the morphological pattern according to Wilson's system (modified from Hardy) had no statistically significant correlation with DS degree of descent.Presence of residual tumor on postoperative magnetic resonance images was significantly correlated with Wilson's classification and with supradiaphragmatic tumor height.On the other hand,cerebrospinal fluid leak showed no statistically significant difference between variable degrees of DS descent.Volumetric data of the tumor portion above the diaphragma opening are more important than morphological data for prediction of surgical field block caused by descended DS.While DS prolapse significantly increases the difficulty of the operative procedure,residual tumor presence is mainly dependent on morphological classification,especially cavernous sinus invasion.

关 键 词：diaphragma sellae PITUITARY MACROADENOMA TRANSSPHENOIDAL surgery CEREBROSPINAL fluid LEAK 

分 类 号：R[医药卫生]