CEREBROSPINAL

作品数：131被引量：212H指数：7
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相关机构：首都医科大学第四军医大学西京医院南方医科大学南方医院泗洪县人民医院更多>>
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Functional abnormalities of the glymphatic system in cognitive disorders
《Neural Regeneration Research》2025年第12期3430-3447,共18页Wuyue Shentu Qi Kong Yier Zhang Wenyao Li Qiulu Chen Sicheng Yan Junjun Wang Qilun Lai Qi Xu Song Qiao 
supported by Zhejiang Provincial Medical and Health Science and Technology Project,Nos.2022KY008(to JW),2023KY001(to JW),2023KY006(to QL);Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project,No.2023ZL220(to QL)。
Various pathological mechanisms represent distinct therapeutic targets for cognitive disorders,but a balance between clearance and production is essential for maintaining the stability of the brain's internal environm...
关键词：AQUAPORIN-4 ASTROCYTE cerebrospinal fluid dynamics cognitive disorders glymphatic system 
Treatment of a rare and severe infection of central nervous system by Angiostrongylus cantonensis:A case report
《World Journal of Radiology》2025年第2期52-61,共10页Jian-Hui Zhao Wen-Ju Li Jie Jiao Ming-Xing Wang Xi-Mu Zhang Jian-Yuan Yin Wen-Zhi Hu Qing Song Jie Liu 
Supported by the Hainan Provincial Natural Science Foundation of China,No.824MS173 and No.823MS165;the Project of Hainan Province Clinical Medical Center.
BACKGROUND Angiostrongylus cantonensis-induced acute parasitic infection is a rare food-borne disease in clinical practice.Lack of its specific laboratory markers and subsequent difficulty in detecting pathogens cause...
关键词：Angiostrongylus cantonensis Cerebrospinal meningitis Severe infection Central nervous system Metagenomics next generation sequencing Case report 
Epidural pressure measurement using a fiber-optic sensor(proof-of-principle in vivo animal trial)
《Animal Models and Experimental Medicine》2024年第5期769-776,共8页Susanne Barz Marvin Friedemann Sebastian Voigt Markus Melloh Thomas Barz 
Background:An increase in epidural pressure around the stenosis has been observed in patients with lumbar spinal stenosis(LSS)with positive signs of sedimentation or redundant nerve roots.Further analysis of the press...
关键词：ANIMAL CEREBROSPINAL fluid pressure pulse wave velocity SPINAL STENOSIS 
The characteristics of cerebrospinal fluid tumor microenvironment in a patient with leptomeningeal metastases from cancer of unknown primary被引量：1
《Genes & Diseases》2024年第3期39-42,共4页Haoyu Ruan Zhe Wang Xuemei Tang Qiong Zhan Kun Chen Lu Gao Ming Guan 
funded by the National Natural Science Foundationof China(No.82102489,82072367,82120108011).
Cancer of unknown primary(CUP)is a rare disease characterized by metastases in which the primary tumor is of unknown origin.The cerebrospinal fluid(CSF)tumor microenvironment of CUP is still unknown.A Chinese male was...
关键词：METASTASES CEREBROSPINAL FLUID 
Upper extremity motor function before and after the cerebrospinal fluid tap test in patients with idiopathic normal pressure hydrocephalus:A retrospective study
《Chinese Medical Journal》2024年第7期877-879,共3页Caiyan Liu Junji Wei Liling Dong Chenhui Mao Jie Li Xinying Huang Bo Hou Feng Feng Liying Cui Jing Gao 
National Key Research and Development Program of China(No.2020YFA0804500);CAMS Innovation fund for Medical Sciences(No.2016-12 M-1-004);National Natural Science Foundation of China(No.81550021)
To the Editor:Idiopathic normal pressure hydrocephalus(iNPH)patients present disturbances in gait,cognition,and/or control of urination with neuroimaging characterized by enlargement of the cerebral ventricles.Typical...
关键词：PATIENTS CEREBROSPINAL UPPER 
Aquaporin-4 as a cerebrospinal fluid biomarker of Alzheimer’s disease
《Translational Neurodegeneration》2024年第1期215-218,共4页Nerea Gómez de San José Steffen Halbgebauer Petra Steinacker Sarah Anderl-Straub Samir Abu-Rumeileh Lorenzo Barba Patrick Oeckl Giovanni Bellomo Lorenzo Gaetani Andrea Toja Sára Mravinacová Sofia Bergström Anna Månberg Alberto Grassini Innocenzo Rainero Peter Nilsson Lucilla Parnetti Markus Otto 
MO,LP,PN SM and NGSJ are supported by the Marie Skłodowska-Curie grant agreement No.860197—MIRIADE project(European Union’s Horizon 2020 research and innovation program);GB is supported by the Postdoctoral Fellowship for Basic Scientists grant of the Parkinson’s Foundation(Award ID:PF-PRF-934916);LP and LG are funded by the European Union—Next Generation EU—PNRR M6C2—Investimento 2.1 Valorizzazione e potenziamento della ricerca biomedica del SSN(PNRR-MAD-2022–12376035);LB is supported by the Medical Faculty of Martin-Luther University Halle Wittenberg(Junior Clinician Scientist Programm No.JCS24/02);SAB received research support from the Medical Faculty of Martin-Luther University Halle-Wittenberg(Clinician Scientist-Programm No.CS22/06).
The diagnosis of Alzheimer’s disease(AD)relies on the clinical evaluation of patients,often complemented by the analysis of core cerebrospinal fluid(CSF)biomark-ers(Aβ42/40,phosphorylated-Tau and total-tau)[1].Howev...
关键词：CEREBROSPINAL fluid ALZHEIMER TAU diagnosis Aβ 
Alzheimer’s disease early diagnostic and staging biomarkers revealed by large-scale cerebrospinal fluid and serum proteomic profiling被引量：1
《The Innovation》2024年第1期118-126,共9页Qing-Qing Tao Xue Cai Yan-Yan Xue Weigang Ge Liang Yue Xiao-Yan Li Rong-Rong Lin Guo-Ping Peng Wenhao Jiang Sainan Li Kun-Mu Zheng Bin Jiang Jian-Ping Jia Tiannan Guo Zhi-Ying Wu 
This work was supported by grants from the Key Research and Development project of Zhejiang Province(2019C03039);the National Natural Science Foundation of China(81970998);the Science Innovation 2030-Brain Science and Brain-Inspired Intelligence Technology Major Projects(nos.2021ZD0201103 and 2021ZD0201803);the Integrative Traditional Chinese and Western Medicine Innovation Team for Neurodegenerative Diseases of Zhejiang Province.
Amyloid-b,tau pathology,and biomarkers of neurodegeneration make up the core diagnostic biomarkers of Alzheimer disease(AD).However,these proteins represent only a fraction of the complex biological processes underlyi...
关键词：CEREBROSPINAL ALZHEIMER fluid 
Clinical Efficacy of Minimally Invasive Subpial Tonsillectomy(MIST)for Treatment of Chiari Malformation(TypeⅠ)with Syringomyelia
《Brain Science Advances》2023年第4期310-321,共12页Hao Li Zhiqiang Cui Yong Liu 
Background To investigate the clinical efficacy of minimally invasive subpial tonsillectomy(MIST)in the treatment of Chiari malformation(type I)with syringomyelia.Methods A total of 209 Chiari malformation(type I)pati...
关键词：minimally invasive surgery Chiari malformation(typeⅠ) SYRINGOMYELIA cisterna magna reconstruction cerebrospinal fluid circulation 
老年人眼底改变与脑小血管病的相关性被引量：1
《脑与神经疾病杂志》2023年第10期653-656,共4页贺沁飞 贺一杰 李泽 杨柏楠 吴云 
黑龙江省博士后资助项目(LBH-Z16306)。
视网膜作为中枢神经的延续,其在解剖、功能、损伤反应以及免疫学方面表现出与神经系统相似的特征。如眼底有与血-脑脊液屏障(blood-cerebrospinal fluid barrier,BCFB)结构相似的血-视网膜屏障(blood retinal barrier,BRB)。BCFB的损伤...
关键词：脑小血管病 免疫学方面 视网膜组织 眼底改变 间接反应 损伤反应 CEREBROSPINAL BARRIER 
Detection of meningeal carcinomatosis by metagenomic next-generation sequencing and copy number variation analysis of cerebrospinal fluid
《China Medical Abstracts(Internal Medicine)》2023年第3期190-190,共1页任海涛 
Objective To evaluate the significance of copy number variation(CNV)and metagenomic nextgeneration sequencing(mNGS)of cerebrospinal fluid(CSF)in the diagnosis of meningeal carcinomatosis(MC).Methods Ten patients with ...
关键词：CEREBROSPINAL FLUID DIAGNOSIS 
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