荔枝汁对情绪应激大鼠血脂的影响  

Effect of litchi juice on blood lipids in rats under emotional stress

作　　者：郭佑廷 欧阳俊彦[1] 赖玉婷[1] 杨童旺 陆灵婉 傅树宽 柳春红[1,2] 胡卓炎[1] 

机构地区：[1]华南农业大学食品学院,广东广州510642 [2]广东省食品质量安全重点实验室,广东广州510642

出　　处：《食品工业科技》2015年第2期364-367,378,共5页Science and Technology of Food Industry

基　　金：国家荔枝龙眼产业技术体系(CARS-33);广东省科技计划项目(2012B090600005;2012B091400001);农业部农产品质量安全风险评估专项(GJFP2014011)

摘　　要：目的:研究荔枝汁对情绪应激大鼠血脂代谢的调节作用。方法:将24只雄性SD大鼠随机分为3组:对照组、模型组、荔枝汁组,采用不确定性空瓶刺激的方法建立大鼠焦虑模型,造模前分别给予大鼠灌服生理盐水(对照组、模型组)、荔枝汁(荔枝汁组),14d后利用旷场实验测试大鼠行为,随后测定大鼠血浆甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)水平,并计算非高密度脂蛋白胆固醇(non-HDL-C)含量、TG/HDL-C、LDL-C/HDL-C的比值。结果:对照组体质量及食物利用率极显著高于其余各组(p<0.01);各组大鼠总运动距离及直立次数差异无显著性(p>0.05),模型组中央区停留时间以及中央区进入次数均显著低于对照组和荔枝汁组(p<0.05),模型组修饰次数显著高于荔枝汁组(p<0.05);模型组的血浆TC显著高于对照组(p<0.05)、non-HDL-C显著高于对照组和荔枝汁组(p<0.05)、LDL-C极显著高于对照组(p<0.01);模型组的血浆TG/HDL-C显著低于对照组(p<0.05);荔枝汁组的血浆HDL-C显著高于对照组和模型组(p<0.05);在血浆LDL-C/HDL-C方面,模型组极显著地高于对照组和荔枝汁组(p<0.01)。结论:荔枝汁能降低焦虑水平并改善血脂代谢。Objective：To research the modulation effects of litchi juice on blood lipids in rats under emotional stress.Methods：Male Sprague-Dawley rats were divided into 3 groups randomly：control group,model group,litchi juice group. The rat model of emotional stress was induced by randomly giving empty water bottles. The rats were administered with saline（control group,model group） or litchi juice（litchi juice group）. 14 d later,animal behaviors were assessed in the open field test,and TG,TC,LDL-C and HDL-C were determined. Non-high density lipoprotein-cholesterol（non-HDL-C）,TG/HDL-C and LDL-C/HDL-C ratio were also calculated. Results：The body weight and food utilization rate of control group were higher than those of other groups significantly（p〈0.01）.No significant differences were found for the total distance traveled and the rearing frequency in the open field among the three groups（p〈0.05）. The time spent in the center and the frequency exploration towards to the center of the model group was significantly lower than those of the control and litchi juice groups（p〈0.05）,and the grooming frequency of the model group was significantly higher than that of litchi juice group（p〈0.05）. The plasma TC concentration of model group was significantly higher than that of control group（p〈0.05）. The plasma non-HDL-C concentration of model group was significantly higher than that of the control and litchi juice groups（p〈0.05）,while the LDL-C concentration of model group was significantly higher than that of control group（p〈0.01）. The plasma TG/HDL-C of model group was significantly lower than that of control group（p〈0.05）.The plasma HDL-C concentration of litchi juice group was significantly higher than that of control and model groups（p〈0.05）. The plasma LDL-C/HDL-C of model group was significantly higher than that of control and litchi juice groups（p〈0.01）. Conclusion：Litchi juice may relieve anxiety and improve blood lipids.

关 键 词：荔枝汁 焦虑 血脂 旷场实验 

分 类 号：TS255.1[轻工技术与工程—农产品加工及贮藏工程]