胡萝卜多糖降低血糖的功能研究  

Research on Hypoglycemic Effects of Carrot Polysaccharide

作　　者：阚国仕[1] 杨艳侠[1] 陈红漫[1] 任大明[1] 卢铎 赵迪[1] 

机构地区：[1]沈阳农业大学生物科学技术学院,辽宁沈阳110866

出　　处：《食品研究与开发》2015年第1期118-121,共4页Food Research and Development

基　　金：辽宁省教育厅基金资助(No.L2012238)

摘　　要：探索胡萝卜多糖对糖尿病小鼠血糖水平的影响以及作用机理。对正常小鼠尾静脉注射四嘧啶建立糖尿病小鼠模型,采用格列本脲和不同剂量的胡萝卜多糖溶液对小鼠进行腹腔注射。小鼠体内药理学研究显示胡萝卜多糖能显著降低糖尿病小鼠空腹血糖和糖化血红蛋白含量,增加小鼠肝糖原含量。胡萝卜多糖能降低糖尿病小鼠血糖水平,同时增加糖尿病小鼠肝糖原含量,由此推断其降糖机制可能与体内的糖异生作用有关。To study the impact as well as the mechanism of the carrot polysaccharides on blood glucose levels in type I diabetic mice. type I diabetes mouse model was established by injection of alloxan for normal mouse tail vein,the glibenclamide and different doses of carrots polysaccharide solution were injected by mice intraperitoneal. vivo pharmacology studies have shown that carrots polysaccharide can significantly reduce fasting glucose levels of diabetic mice ,significantly increase the glycogen content of diabetic mice. carrots polysaccharide can reduce fasting glucose of alloxan-induced diabetic mice ,its hypoglycemic mechanism may be relevant to the gluconeogenesis of body .

关 键 词：胡萝卜多糖 降血糖 糖化血红蛋白 肝糖原 

分 类 号：TS201.4[轻工技术与工程—食品科学]