青岛市市北区居民主要邻苯二甲酸酯类物质膳食暴露水平及其风险评估  

Dietary exposure levels and risk assessment of main phthalic acid esters in Shibei District residents,Qingdao

作　　者：于维森[1] 于红卫[1] 吕晓静[1] 赵金泉[2] 郭英兰[1] 辛文静[1] 

机构地区：[1]山东省青岛市疾病预防控制中心,山东青岛266033 [2]青岛大学医学院医学营养研究所,山东青岛266021

出　　处：《中国食品卫生杂志》2015年第2期189-192,共4页Chinese Journal of Food Hygiene

基　　金：青岛市科技局立项(12-1-3-8-nsh)

摘　　要：目的 分析青岛市北区主要食品中邻苯二甲酸二（2-乙基己基）酯（DEHP）和邻苯二甲酸二丁酯（DBP）含量水平,计算本区居民膳食暴露水平并进行初步风险评估。方法 全区采集7类样品共281份,采用气相色谱-质谱法测定食品中DEHP和DBP的含量。利用食品中DEHP和DBP的平均含量,同时结合居民平均食物消费量,计算7类食品的DEHP和DBP的膳食暴露水平,并分别与DEHP和DBP的每日可耐受摄入量（tolerable daily intake,TDI）比较,初步评估市北区居民主要食品中DEHP和DBP的暴露风险。结果 7类食品中DEHP和DBP的含量范围分别为0.00~5.90和0.00~7.20 mg/kg BW。市北区居民经7类食品中DEHP和DBP暴露量分别为0.006 927和0.005 558mg/kg BW,均未超过相应的TDI。结论 市北区居民经7类食品摄入DEHP和DBP的的健康风险较低。Objective To analyze the content of dibutyl phthalate and bis（2-ethylhexyl） phthalate in main food, and assess the risk of dietary exposure of residents in Shibei District. Methods A total of 281 samples were collected from seven food categories and the identification and quantification were performed by GC-MS in selected ion monitoring （SIM） mode. The dibutyl phthalate and bis（2-ethylhcxyl） phthalate exposure was estimated by the food consumption data. The health risk was assessed by comparing the dibutyl phthalate and bis（2-ethylhexyl） phthalate exposure with tolerable daily intake （TDI） and the margins of safety （MOS）. Results In accordance with the mean value of food consumption estimates, the dibutyl phthalate and bis（2-ethylhexyl） pbthalate exposure of Shibei District residents from 7 major food categories were 0. 006 899 and 0. 005 526 mg/kg BW, and didn＇t exceed the TDI. The MOS values were 7.2 and 1.8, both above 1. Conclusion In Shibei District, the phthalic acid esters in seven food categories were not intentionally adulterated. The contamination of phthalic acid ester had covered most of the food. The risk was low at present but further study about the long-term exposure was needed.

关 键 词：邻苯二甲酸酯 邻苯二甲酸二丁酯 邻苯二甲酸二(2-乙基己基)酯 风险评估 食品安全 

分 类 号：R155.5[医药卫生—营养与食品卫生学] O17[医药卫生—公共卫生与预防医学]