卒中后痴呆的预防和治疗  

Prevention and treatment of poststroke dementia

作　　者：李姗姗[1] 徐运[2] 

机构地区：[1]南京医科大学鼓楼临床医学院,210008 [2]南京医科大学鼓楼临床医学院神经内科,210008

出　　处：《国际脑血管病杂志》2015年第3期198-203,共6页International Journal of Cerebrovascular Diseases

基　　金：国家自然科学基金重大项目（81230026）

摘　　要：卒中后痴呆发病率高，疾病负担重，预防或延缓其发生和进展十分重要。近年来，针对血管危险因素进行干预、坚持饮食管理以及功能锻炼等生活方式调整已被证实能在一定程度上预防卒中后痴呆。胆碱酯酶抑制药、谷氨酸受体拮抗药等药物在延缓卒中后痴呆和血管性认知损害的发展方面发挥着重要作用。文章就卒中后痴呆的预防和治疗最新研究进展进行了综述。The incidence of poststroke dementia is high and the burden of disease is heavy. It is very important to prevent or delay its occurrence and progression. In recent years, the lifestyle adjustments, such as the intervention for vascular risk factors, adhering to the diet management, and functional exercise have been confirmed to prevent poststroke dementia to a certaln extent. Acetylcholinesterase inhibitor and glutamate receptor antagonist, etc. play an important role in delaying the progression of poststroke dementia and vascular cognitive impalrment. This article reviews the latest progress in research on the prevention and treatment of poststroke dementia.

关 键 词：卒中 痴呆 血管性 认知障碍 胆碱酯酶抑制药 危险因素 膳食 锻炼 

分 类 号：R749.13[医药卫生—神经病学与精神病学]