多囊肝的病因、诊断及治疗的研究进展  

Research progress on etiology,diagnosis and treatment of polycystic liver

作　　者：王芹芹[1] 熊伍军[1] 

机构地区：[1]同济大学附属东方医院肝脏科,上海200120

出　　处：《同济大学学报（医学版）》2015年第2期129-132,共4页Journal of Tongji University(Medical Science)

基　　金：上海市浦东新区卫生系统重点专科项目(QJ020)

摘　　要：多囊肝是一种常染色体显性遗传疾病,常与成人多囊肾伴发,早期常无症状,很少影响肝功能,但随病情发展,可出现腹胀、腹痛及腹部包块,影响患者的正常生活。其病因及发病机制尚不明确,目前临床上的治疗方法都不太理想。本研究回顾了近几年国内外有关文献,主要对多囊肝的病因、危险因素、分级、诊断及治疗作一综述,用于指导临床诊断及治疗。Polycystic liver disease is an autosomal dominant genetic disease, often associated with adult polycystic kidney disease. The disease is often asymptomatic in the early stage, rarely affects liver function, but with the progression of the disease, there may be bloating, abdominal pain and abdominal mass, affecting normal life of patients. The etiology and pathogenesis are not clear, and the clinical treatments are less desirable. This article reviews the recent literatures published at home and abroad on the main cause, risk factors, classification, diagnosis and treatment of polycystic liver disease.

关 键 词：多囊肝 多囊肾 基因突变 

分 类 号：R575.2[医药卫生—消化系统]