核酸适配体技术在食品有害物检测中的研究进展  

Research Progress of Aptamer in Detecting Harmful Substances in Food

作　　者：卢军利[1,2] 葛玮东 孙建霞[4] 杨勇[2] 焦睿[1] 欧仕益[1] 白卫滨[1] 

机构地区：[1]暨南大学食品科学与工程系,广州510632 [2]四川农业大学食品学院,四川雅安625014 [3]伊梨州妇幼保健院,新疆伊宁835000 [4]广东工业大学轻工化工学院,广州510090

出　　处：《中国农业科技导报》2015年第2期151-158,共8页Journal of Agricultural Science and Technology

基　　金：“十二五”国家科技支撑计划项目(2012BAD36B04);广东高校优秀青年创新人才培育项目(LYM10033)资助

摘　　要：核酸适配体是一段可以特异性识别并结合靶分子的寡聚核苷酸片段,具有亲和力强、稳定性好、易于修饰等特点,已经广泛用于检测、分离纯化和医疗三大领域。基于核酸适配体技术的检测方法得到了迅速地发展,已经应用于小分子、蛋白质、细菌病毒等方面的检测。主要综述了核酸适配体检测食品中有害物的研究进展。Aptamer is an oligonucleotide that can recognize specificity and bind to corresponding targets. It has strong affinity and is highly stable and easier to modify. It has been widely used in detection, separation and purification, medical treatment. The detection assay based on nucleic acid aptamer technology has developed rapidly, and been applied in detecting small molecule, protein, bacteria and viruses, etc.. This paper reviewed the research progress in detecting harmful substances in food by nucleic acid aptamer.

关 键 词：核酸适配体 检测 食品 有害物 

分 类 号：TS201.6[轻工技术与工程—食品科学]