链霉菌生物活性物质分离纯化技术研究进展  

Separation and purification technologies of bioactive metabolites from Streptomyces

作　　者：王凯[1] 李婷 师瑞芳 李师翁[1] 

机构地区：[1]兰州交通大学化学与生物工程学院,甘肃兰州730070 [2]甘肃省极端环境微生物资源与工程重点实验室,甘肃兰州730070 [3]中科院寒区旱区环境与工程研究所,甘肃兰州730030

出　　处：《食品工业科技》2015年第14期373-378,共6页Science and Technology of Food Industry

基　　金：国家自然科学基金资助项目(31260090)

摘　　要：放线菌尤其是链霉菌是微生物生物活性天然产物的主要产生菌,链霉菌属的很多菌能产生多种抗生素、抗肿瘤药物及酶等重要活性代谢产物,具有广泛的商业和医用开发价值。本文对链霉菌产生的生物活性物质分离纯化方法进行了综述,并对发展趋势进行了展望。A large number of bioactive substances,such as antibiotics,antineoplastic drugs and enzymes were mainly derived from actinomycetes,especially from streptomyces. Streptomyces could produce many active metaboiites which had tremendous commercial and medical exploitation value. In this paper,the separation and purification technologies of bioactive microbial metabolites were reviewed and the research trends were discussed.

关 键 词：链霉菌 生物活性物质 分离纯化技术 

分 类 号：TS201.1[轻工技术与工程—食品科学]