黄曲霉毒素B_1半抗原分子设计与抗原合成及抗体特性研究进展  

Research progress in hapten molecule design and immunogen synthesis and antibody characteristics of aflatoxin B_1

作　　者：王亚楠[1,2] 王晓斐[3] 牛琳琳[1,2] 雷壮[1,2] 张海棠[1,2] 王自良[1,2] 

机构地区：[1]河南科技学院动物科技学院,河南新乡453003 [2]动物病毒病防控与药残分析河南省高校重点学科开放实验室,河南新乡453003 [3]河南科技学院新科学院,河南新乡453003

出　　处：《食品工业科技》2016年第23期367-376,共10页Science and Technology of Food Industry

基　　金："十二五"国家科技支撑计划项目(2014BAD13B05)

摘　　要：本文综述了国内外半抗原分子设计方法、基本要求、应遵循原则、抗原合成方法等方面的研究进展,尤其是对黄曲霉毒素B_1(AFB_1)半抗原分子设计与抗原合成及抗体特性进行了详尽阐述,旨在为AFB_1制备AFB_1及其他小分子半抗原高质量的抗体提供新的方法和思路。=To provide new methods and ideas of preparation of high quality antibodies for aflatoxin B1 （AFB1）and other small molecule hapten,the domestic and foreign research progress on molecular design method,the basic requirements, principles to be followed and antigen synthesis methods were reviewed in this paper, in particular, the AFB1 hapten molecule design,antigen synthesis and antibody characteristics were described in detail.

关 键 词：黄曲霉毒素B1 半抗原分子设计 抗原合成 抗体特性 

分 类 号：TS201.1[轻工技术与工程—食品科学]