气相色谱-质谱法在食品药品安全检测中的应用  

Applications of gas chromatography-mass spectrometry in the safety detection of food and drug

作　　者：钱冲[1] 勾新磊[1] 周明强[1,2] 高峡[1,2] 胡光辉[1,2] QIAN Chong GOU Xin-Lei ZHOU Ming-Qiang GAO Xia HU Guang-Hui(Beijing Centre for Physical and Chemical Analysis, Beij＇ing Key Laboratory of Organic Materials Testing Technology ＆ Quality Evaluation, Beijing 100089, China Beijing Academy of Science and Technology Key Laboratory of Analysis and Testing Technology, Beijing 100089, China)

机构地区：[1]北京市理化分析测试中心有机材料检测技术与质量评价北京市重点实验室,北京100089 [2]北京市科学技术研究院分析测试技术重点实验室,北京100089

出　　处：《食品安全质量检测学报》2016年第11期4307-4311,共5页Journal of Food Safety and Quality

摘　　要：气相色谱-质谱法(gas chromatography-mass spectrometry,GC-MS)具有高分离能力、高专属性、高灵敏度,抗干扰能力强,定性、定量分析功能强大等特点,该方法通用性强,操作简便,检测分析快速,已广泛应用于食药安全检测领域。本文主要从农药残留、增塑剂、多环芳烃和基因毒性物质检测4个方面概述了其在食品药品相关国家标准中的应用进展,并结合本部门的实际检测工作,从有机物定性、定量分析,未知化合物纯度、结构分析等方面介绍了其在食药安全检测工作中所取得的成果。Gas chromatography-mass spectrometry （GC-MS） has the advantages of high separation capacity, high specificity, high sensitivity, strong anti-interference ability, strong qualitative and quantitative analysis ability. This method has been already widely used in the field of safety detection of food and drug, which is widely applicable, easily operable, and has fast detection speed. From the four aspects of pesticide residues, plasticizers, polycyclic aromatic hydrocarbons, and genotoxic substances, this paper mainly summarized the application progress of GC-MS in the national standard methods of food and drug. Moreover, according to the practical detection work of our group, from the aspects of the qualitative and quantitative analysis of organics, and the purity and structure analysis of unknown compounds, the achievements of GC-MS in the safety detection work of food and drug were introduced.

关 键 词：气相色谱-质谱法 食品 药品 

分 类 号：TS207.3[轻工技术与工程—食品科学] TQ460.72[轻工技术与工程—食品科学与工程] O657.63[医药卫生—药物分析学]