模拟移动床技术在天然产物分离制备中的应用  

Application of simulated moving bed technology in separation and preparation of natural products

作　　者：王尉[1,2] 林楠[1] 徐双双[1] 赵利新[1] WANG Wei LIN Nan XU Shuang-Shuang ZHAO Li-Xin(Beijing Centre for Physical and Chemical Analysis, Beijing Key Laboratory of Organic Materials Testing Technology ＆ Quality Evaluation, Beijing 100089, China Beijing Academy of Science and Technology Key Laboratory of Analysis and Testing Technology, Beijing 100089, China)

机构地区：[1]北京市理化分析测试中心有机材料检测技术与质量评价北京市重点实验室,北京100089 [2]北京市科学技术研究院分析测试技术重点实验室,北京100089

出　　处：《食品安全质量检测学报》2016年第11期4346-4351,共6页Journal of Food Safety and Quality

摘　　要：随着模拟移动床色谱技术(simulated moving bed,SMB)的快速发展,该技术在天然产物活性成分的提取与纯化中的应用日益广泛。本文简述了SMB技术的发展和在天然产物分离中的应用现状,并重点介绍了SMB技术在黄酮类、多酚类、氨基酸以及肽类和糖类分离制备中的应用。与传统的制备色谱技术相比,SMB采用连续操作手段,具有易于自动化操作、制备效率高、制备量大等特点,在天然产物分离制备中具有良好的发展前景。With the rapid development of simulated moving bed technology （SMB）, SMB has been widely applied to extract and purify active ingredients of natural products. The development and application of SMB in separation and preparation of natural products were reviewed in this paper, and its applications in separation and preparation of flavonoids, polyphenols, amino acids, peptides, and saccharides were mainly introduced. Compared with traditional chromatographic technologies, SMB has good prospects in separation and preparation of natural products due to continuous operation, automation, high efficiency and great yield.

关 键 词：模拟移动床技术 黄酮类 多酚类 氨基酸 肽类 糖类 天然产物 分离 

分 类 号：O658[理学—分析化学]