叶下珠酚酸微胶囊的制备  

Preparation of Phyllanthus urinaria Phenolic Acid Microcapsules

作　　者：刘永[1] 陈锦恒 黄佳滨[1] 刘敏纯[1] 詹敏儿 

机构地区：[1]肇庆学院化学化工学院,肇庆526061

出　　处：《食品工业》2017年第5期119-122,共4页The Food Industry

基　　金：广东省教育厅特色创新项目(2014KTSCX192);肇庆市科技计划项目(2014F012);国家级大学生创新创业训练计划项目(201510580009)

摘　　要：以包埋率为优化指标,采用响应面试验优化叶下珠酚酸浓度、壳聚糖浓度和氢氧化钠浓度对叶下珠酚酸微胶囊的制备参数。结果表明:叶下珠酚酸浓度、壳聚糖浓度和氢氧化钠浓度对包埋率影响显著,影响大小顺序为叶下珠酚酸浓度>氢氧化钠浓度>壳聚糖浓度;三因素之间的交互作用都对包埋率影响显著;最佳制备参数为:叶下珠酚酸浓度0.96 mg/mL、壳聚糖浓度7.72 mg/mL、氢氧化钠浓度0.13 mol/L,此条件下提取率为78.98%,与预测值无显著性差异。Using embedding ratio as optimization index, the response surface methodology was used to optimize the preparation process parameters （Phyllanthus urinaria phenolic acid concentration, chitosan concentration and sodium hydroxide concentration） ofPhyllanthus urinaria phenolic acid microcapsules. The results showed that these three factors had significantly effect on the embedding ratio, and the interactions between these three factors had also significantly effect on embedding ratio; The effect of the factors on embedding ratio was in order ofPhyllanthus urinaria phenolic acid concentration, sodium hydroxide concentration and chitosan concentration; The optimal preparation parameters were Phyllanthus urinaria phenolic acid concentration of 0.96 mg/mL, chitosan concentration of 7.72 mg/mL and sodium hydroxide concentration of 0.13 mol/L, under which the embedding ratio was 78.98% and there was no significant difference with prediction value.

关 键 词：叶下珠 酚酸 微胶囊 

分 类 号：TQ461[化学工程—制药化工]