一种脂肪酶催化合成蔗糖酯反应的工艺优化  

A study on a lipase catalyzed synthesis of sucrose ester reaction

作　　者：杜理华[1] 沈乐[1] 蒋志鹏[1] 

机构地区：[1]浙江工业大学药学院,浙江杭州310014

出　　处：《浙江工业大学学报》2017年第3期285-288,共4页Journal of Zhejiang University of Technology

基　　金：国家自然科学基金资助项目(21306172);国家948计划资助项目(2014-4-29);浙江省自然科学基金资助项目(LY17B020010);浙江省公益农业计划项目(2014C32094)

摘　　要：以脂肪酶TL IM(Thermomyceslanuginosus)为催化剂,以DMSO/叔戊醇为溶剂催化合成蔗糖与乙酸乙烯酯反应.实验系统地研究了脂肪酶催化合成蔗糖酯的影响因素,对溶剂比、底物的摩尔比、反应温度和时间进行探讨.研究结果表明:溶剂、底物摩尔比、温度及反应时间等方面对蔗糖酯化反应有不同程度上的影响.Experiment with lipase TL IM as catalyst, DMSO and tert-amyl alcohol as the reaction system catalytic synthesis of sucrose and vinyl acetate. The influencing factors of lipase catalyzed synthesis of sucrose esters were studied in the experiment. The molar ratios of solvents and substrates, reaction temperature and time were investigated. The results show that all the molar ratios of bothsolvents and substrates, temperature and reaction time have different degree of influenceon the sucrose esterification reaction.

关 键 词：脂肪酶 蔗糖酯 酯化反应 催化 

分 类 号：R931.6[医药卫生—生药学]