神经系统发作性疾病的脑磁图研究进展  

Research progress of magnetoencephalography in neurological paroxysmal disease

作　　者：詹飞霞 曹春燕[2] 曹立[1] ZHAN Fei-xia;GAO Chun-yan;CAO Li(Department of Neurology,Ruo＇in Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China;Department of Functional Neurosurgery,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China)

机构地区：[1]上海交通大学医学院附属瑞金医院神经内科,上海200025 [2]上海交通大学医学院附属瑞金医院功能神经外科,上海200025

出　　处：《上海交通大学学报（医学版）》2018年第8期979-983,共5页Journal of Shanghai Jiao tong University:Medical Science

基　　金：国家自然科学基金(81571086);上海市教育委员会高峰高原学科建设计划(20161401);上海交通大学多学科交叉项目培育(医工)(YG2016MS64)~~

摘　　要：神经系统发作性疾病是一大类具有突发性、反复性、自限性等特点的临床综合征。其临床发作间期,常规生化或影像学检查发现患者通常无明显异常。脑磁图(magnetoencephalography,MEG)作为一种重要的研究脑磁信号、监测脑电活动的电生理工具,可通过超导量子干涉仪对人脑进行非侵入性的检测,具有较高的时间和空间分辨率,已逐渐应用于神经精神系统疾病及大脑高级活动的功能及机制研究。该文主要对癫痫、发作性运动诱发性运动障碍、偏头痛等常见神经系统发作性疾病的MEG应用及研究做一综述。Neurological paroxysmal disease is a large group of clinical syndrome with a characteristic of sudden, recurrent, self-limiting. Clinically, routine biochemical or imaging examinations are usually with no significant abnormalities in the interictal period. However, magnetoencephalography （MEG）, as an important electrophysiological tool in studying brain magnetic signals and monitoring brain electric activity, has highly temporal and spatial resolution for its noninvasive measurement of human brain with superconducting quantum interference. Therefore, it has been gradually used in researching for functional activities and mechanisms of the neuropsychiatric disorders and the advanced brain activity. There mainly reviewed the application and studies of MEG in epilepsy, paroxysmal kinesigenic dyskinesias and migraine.

关 键 词：发作性疾病 癫痫 发作性运动诱发性运动障碍 偏头痛 脑磁图 

分 类 号：R741.044[医药卫生—神经病学与精神病学]