非参数概率法评估2015—2017年深圳地区9类食品黄曲霉毒素膳食暴露风险  

Dietary exposure assessment to aflatoxins in nine kinds of foodstuff by Mont Carlo non-parametric probability approach in Shenzhen City

作　　者：李可[1] 陈网璇 丘汾[1] 梁肇海[1] 杨梅[1] 王舟[2] Li Ke;Chen Wangxuan;Qiu Fen;Liang Zhaohai;Yang Mei;Wang Zhou(Center for Disease Control and Prevention of Futian District Shenzhen City,Shenzhen 518040,China)

机构地区：[1]深圳市福田区疾病预防控制中心,深圳518040 [2]深圳市疾病预防控制中心

出　　处：《卫生研究》2018年第5期827-832,共6页Journal of Hygiene Research

基　　金：广东省科技计划项目(No.2015A30302008);深圳市科技计划项目(No.JCYJ20150402150147470)

摘　　要：目的对深圳居民通过市售9类食品产生的黄曲霉毒素膳食暴露及其健康风险进行评价。方法 2015年3月至2017年11月收集深圳地区10个行政区9大类26种1038份食品样品,利用食品中黄曲霉毒素(AFT)污染水平数据和当地居民膳食消费数据,使用蒙特卡洛非参数评估方法,评估食品中黄曲霉毒素对深圳地区人群健康的影响。结果深圳地区居民全人群9类食品黄曲霉毒素平均暴露量和高消费暴露量分别为0.8533 ng/(kg·BW·d)和2.1646 ng/(kg·BW·d);对黄曲霉毒素B1(AFB1)平均暴露量和高消费暴露量分别为0.5113 ng/(kg·BW·d)和1.3264 ng/(kg·BW·d);AFB1膳食摄入增加肝癌年发病率为0.0199/万人和0.0517/万人。深圳地区黄曲霉毒素膳食摄入主要暴露贡献食品为玉米制品、米及米制品、花生油/玉米油。结论深圳地区膳食中黄曲霉毒素引发肝癌的总体健康风险较低,但应持续监管特殊人群主要暴露贡献食品的暴露水平。Objective To assess Shenzhen residents＇ dietary exposure to aflatoxins from 9 kinds of foods and health risk. Methods Dietary intake of aflatoxins from local concentration data and foodstuff consumption data was simulated by Mont Carlo non- parametric probability approach. Results Aflatoxins （AFT） average intake and high intake were 0. 8533 ng/（ kg·BW·d ） and 2. 1646 ng/（ kg·BW·d ）, respectively. Aflatoxin B1 （AFB1）average level intake and higher level intake were 0.5113 ng/（ kg·BW·d）and 1. 3264 ng/（kg·BW·d）, respectively. The potential risk for cancer using average data was estimated at 0.0199 people/（ ten thousand people- year）, even though this was 0. 0517 people/（ ten thousand people, year）in higher level. Major exposure contribution to food were corn and products, rice and products, and peanut oil, corn oil. Conclusion The current dietary intake of AFB1 and AFT in Shenzhen has no appreciable effect on health. Government action should be maintained and improved in order to guarantee, aiming at major exposure contribution to food, that special human exposure levels are kept was low as possible.

关 键 词：黄曲霉毒素 暴露评估 癌症风险 食品检测 

分 类 号：R155.51[医药卫生—营养与食品卫生学] TS207.4[医药卫生—公共卫生与预防医学]