Blood exosomes as a tool for monitoring treatment efficacy and progression of neurodegenerative diseases  

Blood exosomes as a tool for monitoring treatment efficacy and progression of neurodegenerative diseases

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作  者:Hanin Abdel-Haq 

机构地区:[1]National Center for Drug Research and Evaluation, Istituto Superiore di Sanità

出  处:《Neural Regeneration Research》2019年第1期72-74,共3页中国神经再生研究(英文版)

摘  要:Alzheimer’s disease,Parkinson’s disease,Huntington’s disease,amyotrophic lateral sclerosis,and prion disease are representative neurodegenerative diseases that share common sub-cellular features,the most obvious of which is a strong association with the accumulation of misfolded,aggregated,and insoluble forms of proteins in the brain,as evidenced in post-mortem brain tissues of patients.Diagnosis of neurodegenerative diseases is oftenAlzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and prion disease are representative neurodegenerative diseases that share common sub-cellular features, the most obvious of which is a strong association with the accumulation of misfolded, aggregated, and insoluble forms of proteins in the brain, as evidenced in post-mortem brain tissues of patients.

关 键 词:疾病 治疗功效 CELLULAR 工具 PRION 蛋白质 大脑 

分 类 号:R741[医药卫生—神经病学与精神病学]

 

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