CELLULAR

作品数:854被引量:1694H指数:18
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A novel method for clustering cellular data to improve classification
《Neural Regeneration Research》2025年第9期2697-2705,共9页Diek W.Wheeler Giorgio A.Ascoli 
supported in part by NIH grants R01NS39600,U01MH114829;RF1MH128693(to GAA)。
Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subse...
关键词:cellular data clustering dendrogram data classification Levene's one-tailed statistical test unsupervised hierarchical clustering 
Understanding activity of butyrate at a cellular level
《Neural Regeneration Research》2025年第8期2323-2324,共2页Prapti Chakraborty Angela S.Laird 
supported by an NHMRC Project Grant GNT2012895(to ASL)。
Butyrate is a short-chain fatty acid of four carbons in length that is a by-product produced by the microbial fermentation of dietary fiber and undigested carbohydrates within the colon.Over the years,butyrate has att...
关键词:CARBONS BUTYRATE FIBER 
PGLYRP1 protein as a novel mediator of cellular dialogue in neuroinflammation
《Neural Regeneration Research》2025年第7期1993-1994,共2页Anup Bhusal Won-Ha Lee Kyoungho Suk 
supported by a grant from the Basic Science Research Program through the National Research Foundation(NRF),which is funded by the Korean government(MSIP)(NRF-2020M3E5D9079764)(to KS)。
Neuroinflammation has been identified as a crucial element in several neurological disorders. Glial cells play a critical role in directing neuroinflammation, both in deleterious and beneficial ways.
关键词:INFLAMMATION considerably 
The multifaceted role of post-translational modifications of LSD1 in cellular processes and disease pathogenesis
《Genes & Diseases》2025年第3期168-179,共12页Yinrui Li Bo Wang Yichao Zheng Huiqin Kang Ang He Lijuan Zhao Ningjie Guo Hongmin Liu Adil Mardinoglu M.A.A.Mamun Ya Gao Xiaobing Chen 
supported by the Basic Research of Medical Science and Technique Foundation of Henan Province,China(No.SBGJ202301004 to X.B.C.);the Key Project of the High Education from the Education Department of Henan Province,China(No.22ZX008 to Y.C.Z.);the Youth Supporting Program from Henan Province,China(No.2021HYTP060 to Y.C.Z.);the Youth Supporting Program from Zhengzhou University(No.JC202044046 to Y.C.Z.);the Science and Technology Project of Henan Province,China(No.232102311179 to Y.G.);the National Natural Science Foundation of China(No.U21A20416,82020108030 to H.M.L,82103997 to B.W.);the China Postdoctoral Science Foundation(No.2021M692950 to B.W.,2021M702942 to L.J.Z.).
Post-translational modifications(PTMs)of proteins play a crucial role in living organisms,altering the properties and functions of proteins.There are over 450 known PTMs involved in various life activities.LSD1(lysine...
关键词:Enzyme activity Histone demethylase Human diseases LSD1 POST-TRANSLATIONAL 
Mass Spectrometry Imaging for Cellular-level Analysis:Advancesand Applications on Medical Research
《Chemical Research in Chinese Universities》2025年第2期254-265,共12页YU Yile FAN Jinghan LIU Huihui NIE Zongxiu 
supported by the National Natural Science Foundation of China(Nos.22334007,22274160,22304175).
Mass spectrometry(Ms)is widely used in medical applications,such as pharmacokinetics,drug discovery,and clinical diagnostics,as it enables medical researchers and practitioners to gain insights into pathogenic mechani...
关键词:Single cell analysis Cellular-level Matrix-assisted laser desorption ionization mass spectrometry imaging(MALDI-MSI) Secondary ion mass spectrometry(SIMS)-lmaging Desorption electrospray ionization mass spectrometry imaging(DES-MSl) 
Quercetin mitigates iron-induced cell death in chicken granulosa cell
《Journal of Animal Science and Biotechnology》2025年第2期610-630,共21页Shuo Wei Felix Kwame Amevor Xiaxia Du Linxiang Li Zhixin Yi Gang Shu Yan Wang Xiaoling Zhao 
the Innovation and Demonstration of Industry and Education Integration in Feed Industrial Chain Transformation and Upgradation, Sichuan Province, China;the National Key R&D Program of China (Grant No. 2022YFD1600902-4);the National Natural Science Foundation of China (Grant No. 32272870 & 32350410427);the Sichuan Province Central Guided Local Science and Technology Development Special Programme (Grant No. 23ZYZYTS0346);the Sichuan Provincial Natural Science Foundation Outstanding Youth Science Fund Project (Grant No. 24NSFJQ0121);Breeding, Development, and Healthy Breeding of Plum Blossom Chickens in the Bazhong Mountains, a City School Cooperation Project in Bazhong City.
Background Granulosa cell(GC)apoptosis,ferroptosis,and other programmed cell death processes are markers of follicular aging.Quercetin has been shown to reduce ferroptosis,however,its effects on ferroptosis in poultry...
关键词:APOPTOSIS Cellular inflammation Ferroptosis Granulosa cell QUERCETIN 
Cellular therapeutics and immunotherapies in wound healing-on the pulse of time?
《Military Medical Research》2025年第2期242-263,共22页Lioba Huelsboemer Leonard Knoedler Alejandro Kochen Catherine T.Yu Helia Hosseini Katharina S.Hollmann Ashley E.Choi Viola A.Stögner Samuel Knoedler Henry C.Hsia Bohdan Pomahac Martin Kauke-Navarro 
supported by grants from the German Research Foundation (DFG)
Chronic,non-healing wounds represent a significant challenge for healthcare systems worldwide,often requiring significant human and financial resources.Chronic wounds arise from the complex interplay of underlying com...
关键词:Chronic wounds Wound healing Wound healing disorder BIOFILM IMMUNOTHERAPIES Cellular therapies 
Advancing skeletal health and disease research with single-cell RNA sequencing
《Military Medical Research》2025年第2期285-310,共26页Peng Lin Yi-Bo Gan Jian He Si-En Lin Jian-Kun Xu Liang Chang Li-Ming Zhao Jun Zhu Liang Zhang Sha Huang Ou Hu Ying-Bo Wang Huai-Jian Jin Yang-Yang Li Pu-Lin Yan Lin Chen Jian-Xin Jiang Peng Liu 
National Key Research and Development Program of China(2022YFA1103202);National Natural Science Foundation of China(82272507,32270887,and 32200654);Natural Science Foundation of Chongqing(CSTB2023NSCQ-ZDJO008);Postdoctoral Innovative Talent Support Program(BX20220397);Independent Research Project of State Key Laboratory of Trauma and Chemical Poisoning(SFLKF202201);Project for Enhancing Innovation of Army Medical University(2023X1839);Talent Innovation Training Program at the Army Medical Center(ZXZYTSYS09);General Hospital of Western Theater Command Research Project(2021-XZYG-B10);University Grants Committee,Research Grants Council of Hong Kong,China(14113723,N_CUHK472/22,C7030-18G,T13-402/17-N,and AoE/M-402/20)。
Orthopedic conditions have emerged as global health concerns,impacting approximately 1.7 billion individuals worldwide.However,the limited understanding of the underlying pathological processes at the cellular and mol...
关键词:Skeletal disorders Musculoskeletal system Single-cell RNA sequencing(scRNA-seq) Cellular heterogeneity Single cell suspension Bioinformatic analysis 
PROTAR Vaccines: Harnessing Cellular “Shredders” to Outsmart Flu’s Relentless Mutations
《Bulletin of the Chinese Academy of Sciences》2025年第1期60-62,共3页YAN Fusheng 
Imagine a future where a single vaccine could protect you from a multitude of influenza strains,offering broad immunity with minimal risk.This vision is now closer to reality,thanks to a recent study that harnesses th...
关键词:INFLUENZA cellular proteins vaccines MUTATIONS live attenuated vaccines 
A Novel Astrocyte-Neuron Interaction to Control Complex Animal Behavior
《Neuroscience Bulletin》2025年第2期352-354,共3页Helmut Kettenmann 
supported by the Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases(ZDSYS20220304163558001).
A recent publication by Zhou et al.[1]in Neuron demonstrates that a specific interaction between astrocytes and a subtype of neurons has an influence on complex animal behavior,namely risk assessment.The majority of n...
关键词:complex animal behavior NEURON glial cells molecular cellular substrate molecular cellular substrate behavior ASTROCYTE INTERACTION risk assessment 
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