富硒酵母对慢性萎缩性胃炎患者疗效的初步观察  

PRELIMINARY OBSERVATION ON CURING EFFECTS OF SELENIUM RICH YEAST FOR PATIENTS WITH CHRONIC ATROPHIC GASTRITIS(CAG)

作　　者：张廷雨[1] 史奎雄[1] 程五凤[1] 潘碧霞[1] 许秀娴 

机构地区：[1]上海第二医科大学医学营养学教研室

出　　处：《肿瘤》1991年第5期221-224,共4页Tumor

摘　　要：我国是胃癌高发国家,对胃癌的研究发现,慢性萎缩性胃炎(CAG)是胃癌的癌前变化,有报道随访十年其转癌率达10％左右。在哥伦比亚,胃癌高发区人群中患CAG的比例远高于低发区。我国胃癌流行病学综合考察队研究发现:CAG调整患病率与胃癌调整死亡率呈正相关。而这类患者的硒水平随胃粘膜病变的加重逐渐降低。A group of CAG patients treated by selenium rich yeast (150μg/d) and 16,cases ofcontrol were observed. Comparing the changes after 10 weeks in the activities of SOD, MnSOD,NK Cell and the content of Se and LPO of blood of the treated group with those ofthe control group,we found that the serum selenium level increased in treated group andwas significantly higher than those in control group, while the decrease of activity ofMnSOD was also significantly larger than that of the control. The activity of NK cellin peripheral blood in the treated group had a tendency to increase but the differencewas not significant statistically. The symptoms of CAG patients were alleviated, but nosignificant difference was observed with the control group. The pathological changes ingastric mucosa in the treated group tended to improve better, but due to the number ofpersons examined by endoscope after treatment was too small and the period observedwas only 10 weeks,we can not yet draw a definite conclusion. The above data showedthat the selenium rich yeast was beneficial in the treatment of CAG patients.

关 键 词：酵母 慢性 萎缩性胃炎 硒 

分 类 号：R573.32[医药卫生—消化系统]