阿克苏灰枣生物活性成分的免疫交互作用  

Immune Interaction of Bioactive Components in Ziziphus jujuba cv. Huizao Fruits from Aksu

作　　者：邹曼[1] 张玉环[1] 陈义伦[1] 马新凤[1] 王桂欣 马超 朱风涛 ZOU Man;ZHANG Yuhuan;CHEN Yilun;MA Xinfeng;WANG Guixin;MA Chao;ZHU Fengtao(Key Laboratory of Food Processing Technology and Quality Control in Shandong Province,College of Food Science and Engineering,Shandong Agricultural University,Taian 271000,China;Jinan Fruit Research Institute,All China Federation of Supply and Marketing Cooperatives,Jinan 250014,China)

机构地区：[1]山东农业大学食品科学与工程学院,山东省高校食品加工技术与质量控制重点实验室,山东泰安271000 [2]中华全国供销总社济南果品研究院,山东济南250014

出　　处：《食品科学》2018年第7期201-206,共6页Food Science

基　　金：“十二五”国家科技支撑计划项目(2012BAD36B07-04)

摘　　要：实验以阿克苏灰枣中提取分离得到的多糖、多酚和三萜类化合物为对象,通过小鼠灌胃实验,研究其生物活性成分及其两两组合对小鼠免疫脏器指数、碳粒廓清速率、血清溶血素抗体生成和绵羊红细胞诱导的迟发型超敏反应的影响以及其组合的免疫交互作用。结果表明:灰枣多糖、多酚和三萜类化合物均可显著提高小鼠体内免疫器官指数、半数溶血值、吞噬指数α以及小鼠足跖厚度,具有增强小鼠细胞免疫、体液免疫以及非特异性免疫的作用;多糖和多酚具有协同免疫作用,多糖和三萜类化合物具有拮抗免疫作用,多酚和三萜类化合物具有加和免疫作用。The effects of intragastric administration of bioactive components such as polysaccharides,polyphenols and triterpenoids extracted from Ziziphus jujuba cv.Huizao fruits grown in Aksu alone and their combinations on mouse immune organ indexes,phagocytic index,antibody-producing capacity and delayed type hypersensitivity(DTH)to sheep red blood cells(SRBC)were studied in this work.The results showed that the polysaccharides,polyphenols and triterpenoids could significantly improve immune organ indexes,serum half hemolysis value(HC50),phagocytic index and footpad thickness,and enhance cellular and humoral immune responses and nonspecific immune responses in mice.The polysaccharides had synergistic immunoregulatory effects with the polyphenols.Moreover,the polysaccharides had an antagonistic interaction with the triterpenoids,and their effects were additive.

关 键 词：阿克苏灰枣 免疫 多糖 多酚 三萜类化合物 交互作用 

分 类 号：TS201.4[轻工技术与工程—食品科学]