火炬树芽的减肥降脂功能分析  

Functions of Rhus typhina sprout in reducing obesity and blood lipids

作　　者：王莹[1] 王思予[1] 申秀娟 张磊[1] 徐亚杰[1] 刘斌[1] 李大军[1] WANG Ying;WANG Siyu;SHEN Xiujuan;ZHANG Lei;XU Yajie;LIU Bin;LI Dajun(College of Food Science,Jilin Agricultural University,Changchun,Jilin 130118,China)

机构地区：[1]吉林农业大学食品科学与工程学院,吉林长春130118

出　　处：《西北农林科技大学学报（自然科学版）》2018年第9期115-120,共6页Journal of Northwest A&F University(Natural Science Edition)

基　　金：吉林省林业科技项目(2011-04)

摘　　要：【目的】研究火炬树芽对高脂模型小鼠的降血脂、减肥及护肝作用,为其开发利用提供参考。【方法】测算火炬树芽的水分含量及多糖、总黄酮、皂苷得率。取昆明小鼠60只,雌雄各半,随机分组。将质量分数0%,2.5%,5%和10%火炬树芽掺入到高脂饲料中,对4组高脂模型小鼠进行饲喂,以基础鼠粮作为空白对照,高脂饲料中掺入质量分数2.5%的柳树叶作阳性对照,研究火炬树芽对高脂模型小鼠血清中甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)含量,肝脏总超氧化物歧化酶(T-SOD)和谷胱甘肽过氧化物酶(GSH-Px)活性、丙二醛(MDA)含量、肝脏指数及小鼠体质量的影响。【结果】火炬树芽水分质量分数为60%,干品多糖得率为3.47%,总黄酮得率为3.19%,皂苷得率为2.43%。与对照组小鼠相比,2.5%、5%和10%火炬树芽处理组小鼠体质量及血清TG、TC、LDL-C水平均明显降低,HDL-C含量显著或极显著升高,肝脏指数显著或极显著降低;10%火炬树芽组与2.5%柳树叶处理组小鼠相比,肝脏指数降低,T-SOD和GSH-Px活性极显著升高(P<0.01),MDA含量有所下降。【结论】火炬树芽含有丰富的具有保健功能的活性物质,能够减轻高血脂试验动物的肝脏负担,对高脂模型小鼠具有明显的降血脂减肥作用,并能增强高脂模型小鼠的肝脏抗氧化能力。【Objective】The lipid-lowering,weight loss and liver protection of hyperlipidemia mice were studied with Rhus typhina sprout as feed supplement to provide reference for its development and utilization.【Method】The contents of water,yield of polysaccharides,total flavonoids and saponins of the sprout were determined.A total of 60 Kuming mice(male and female)were randomly divided.The sprout of Rhus typhina was incorporated into high-fat rat food at mass fractions of 0%,2.5%,5%and 10%,while common animal basal food was set as normal group and that with willow leaves mass fraction of 2.5%was set as positive control group.Then,the changes of body weight,TG,TC,LDL-C,HDL-C levels and liver index,T-SOD,GSH-Px activity and MDA content in liver of hyperlipidemic mice were analyzed.【Result】The examined sprout of Rhus typhina contained 60%water,and the dried product yields of polysaccharides,total flavonoids and saponins were 3.47%,3.19%and 2.43%,respectively.Compared with the 0%sprout treatment,the body weights as well as serum TG,TC and LDL-C of mice with other sprout treated food decreased extremely significantly(P<0.01),while HDL-C increased extremely significantly(P<0.01).The liver index of the sprout treatments decreased significantly compared with the 0%sprout treatment and that of the 10%sprout treatment was less than that of the 2.5%willow treatment.The T-SOD and GSH-Px activities in the 10%sprout level treatment were higher than those in the 0%treatment(P<0.01),while MDA contents decreased.【Conclusion】The sprout of Rhus typhina can alleviate the liver burden caused by hyperlipidemia,reduce the blood lipids and obesity of hyperlipidemic mice,and improve the antioxidant capacity.

关 键 词：火炬树芽 减肥 降脂 抗氧化 

分 类 号：TS201.4[轻工技术与工程—食品科学]