Protecting kidneys in liver transplant patients:A pathway to preventive interventions  

作　　者：Lena Sibulesky Scott W Biggins Raimund Pichler 

机构地区：[1]Division of Transplant Surgery,Department of Surgery,University of Washington,Seattle [2]Division of Gastroenterology and Hepatology,Department of Medicine,University of Washington [3]Division of Nephrology, Department of Medicine,University of Washington,Seattle

出　　处：《World Journal of Hepatology》2018年第9期637-638,共2页世界肝病学杂志（英文版）（电子版）

摘　　要：Acute kidney injury(AKI) is a frequent postoperative complication after liver transplantation. The etiology is multifactorial,including perioperative renal status,surgery related events,and postoperative immunosuppression therapy. The role of renal hypoperfusion and hepatic ischemia-reperfusion injury as causes of early AKI are now being increasingly recognized. Further studies should focus on therapies that would attenuate this injury.Acute kidney injury(AKI) is a frequent postoperative complication after liver transplantation. The etiology is multifactorial,including perioperative renal status,surgery related events,and postoperative immunosuppression therapy. The role of renal hypoperfusion and hepatic ischemia-reperfusion injury as causes of early AKI are now being increasingly recognized. Further studies should focus on therapies that would attenuate this injury.

关 键 词：Acute KIDNEY INJURY Liver transplantation Hepatic ISCHEMIA-REPERFUSION INJURY MARGINAL GRAFTS Small interfering ribonucleic acid 

分 类 号：R[医药卫生]