Value of preoperative MRI for prostate cancer staging and continence outcomes prior to prostatectomy: A review of the literature  

作　　者：Eric D Andresen James A Brown Kenneth G Nepple 

机构地区：[1]Department of Urology, University of Iowa

出　　处：《World Journal of Clinical Urology》2015年第1期56-63,共8页世界临床泌尿杂志

摘　　要：Pelvic imaging in newly diagnosed prostate cancer is primarily used for staging prior to definitive treatment. Over the past decade use of magnetic resonance imaging(MRI) for pre-surgical planning has increased, as well has he technology and methods for performing prostate MRI. To investigate and define the different MRI technologies available and further assess MRI technology ability to predict pathologic stage. Searching Pub Med, we identified current published literature,where the cohort population underwent pre-operative MRI followed by prostatectomy. Keywords used in the Pub Med literature search included: MRI, prostate cancer, prostate cancer staging, multiparamentric MRI and incontinence. Papers were included for review if they discussed use of MRI prior to prostatectomy and had corresponding pathologic data, staging, incontinence, and surgical outcomes. Primary information noted was MRI sensitivity, specificity and overall accuracy for detecting extracapsular extension(ECE) and seminal vesicle involvement(SVI). Secondary information derived included assessing the surgical influence of staging information, and identifying predictors of urinary incontinence recovery. Review of the literature showed that in regards to extracapsular extension the reported MRI accuracy ranged from 76%-98%, sensitivity from 20%-90% and specificity from 82%-99%. As for seminal vesicle involvement the reported MRI accuracy ranged from 76%-98%, sensitivity from 20%-90% and specificity from 82%-99%. There is a widely varying sensitivity and specificity for both ECE and SVI and the wide variability in the MRI technology used in the literature supports that use of MRI technology for prostate cancer remains investigational.Pelvic imaging in newly diagnosed prostate cancer is primarily used for staging prior to definitive treatment. Over the past decade use of magnetic resonance imaging(MRI) for pre-surgical planning has increased, as well has he technology and methods for performing prostate MRI. To investigate and define the different MRI technologies available and further assess MRI technology ability to predict pathologic stage. Searching Pub Med, we identified current published literature,where the cohort population underwent pre-operative MRI followed by prostatectomy. Keywords used in the Pub Med literature search included: MRI, prostate cancer, prostate cancer staging, multiparamentric MRI and incontinence. Papers were included for review if they discussed use of MRI prior to prostatectomy and had corresponding pathologic data, staging, incontinence, and surgical outcomes. Primary information noted was MRI sensitivity, specificity and overall accuracy for detecting extracapsular extension(ECE) and seminal vesicle involvement(SVI). Secondary information derived included assessing the surgical influence of staging information, and identifying predictors of urinary incontinence recovery. Review of the literature showed that in regards to extracapsular extension the reported MRI accuracy ranged from 76%-98%, sensitivity from 20%-90% and specificity from 82%-99%. As for seminal vesicle involvement the reported MRI accuracy ranged from 76%-98%, sensitivity from 20%-90% and specificity from 82%-99%. There is a widely varying sensitivity and specificity for both ECE and SVI and the wide variability in the MRI technology used in the literature supports that use of MRI technology for prostate cancer remains investigational.

关 键 词：Magnetic resonance imaging Metastasis Urinary INCONTINENCE PROSTATE cancer Seminal VESICLE invasion EXTRACAPSULAR extension 

分 类 号：R[医药卫生]